Colony-Stimulating Factors
Crc Press Inc (Verlag)
978-0-8247-9492-7 (ISBN)
Concentrating on proven data and adopting a structure-function approach, this text provides grounding for an intricate understanding of the molecular biology, physiological mechanisms, and routine clinical use in disease settings of colony-stimulating factors (CSFs). This edition includes eight additional chapters, with updates of recently-discovered and established CSFs, each indexed individually.
John M. Garland/,
Overview: introduction to the haematopoietic system; surrogate assays for haematopoietic stem cell activity; receptors for haematopoietic regulators; regulation of the cell cycle by kinases and cyclins; gene organization and regulation; cytokines and apoptosis - the mechanism of regulation of cell death; haematopoietic microenvironments; extracellular matrix- and membrane-bound cytokines; transfection of stem cells and gene therapy. Colony-stimulating factor: granulocyte-macrophage colony-stimulating factor and its receptor; granulocyte colony-stimulating factor; human interleukin-3 - an overview; macrophage colony-stimulating factor; erythropoietic; the role of interleukin-4 in normal and malignant human haematopoietic effects of interleukin-1; kit-ligand-stem cell factor; interleukin-5. Cytokines: macrophages inflammatory protein-1 alpha; transforming growth factor-beta, tumour necrosis factor-alpha, and macrophage inflammatory protein-1 alpha are bidirectional regulators of haematopoietic cell growth; leukaemia inhibitory factor; interleukin-12 in haematopoiesis; ex vivo expansion of haematopoietic stem and progenitor cells; clinical use of cytokines.
| Erscheint lt. Verlag | 16.5.1997 |
|---|---|
| Verlagsort | Bosa Roca |
| Sprache | englisch |
| Maße | 178 x 254 mm |
| Gewicht | 1179 g |
| Themenwelt | Studium ► 1. Studienabschnitt (Vorklinik) ► Histologie / Embryologie |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| ISBN-10 | 0-8247-9492-3 / 0824794923 |
| ISBN-13 | 978-0-8247-9492-7 / 9780824794927 |
| Zustand | Neuware |
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