The Duration and Safety of Osteoporosis Treatment (eBook)

Anabolic and Antiresorptive Therapy

Stuart Silverman, Bo Abrahamsen (Herausgeber)

eBook Download: PDF

2015 | 1st ed. 2016
XVI, 338 Seiten
Springer International Publishing (Verlag)
978-3-319-23639-1 (ISBN)

Infos

Providing a comprehensive review of short-and long-term adverse events of both antiresorptive and anabolic drugs, this practical guide updates the clinician on the pathophysiology of osteoporosis and the principles behind our present and future pharmaceuticals. Leading practitioners in the field examine all current literature and data regarding the duration and safety of these therapies, with recommendations for clinicians on decision-making and best practices for osteoporosis patients. An overview of the pathophysiology and epidemiology of osteoporosis and discussion of both anabolic and antiresorptive drugs is followed by fracture risk assessment and an examination of treatment failures. Next, a number of chapters are dedicated to the diagnosis, presentation and management of atypical femur fractures and osteonecrosis of the jaw (ONJ), each of which are significant patient concerns when using these osteoporosis treatments. The introduction and utilization of drug holidays is also discussed, as well as the long-term outlook for management of osteoporotic patients. Written and edited by experts in the field, The Duration and Safety of Osteoporosis Treatment is a balanced resource for researchers, practitioners and policy-makers alike for clinical decision-making and patient care. 

Stuart L. Silverman, MD, FACP, FACR

Cedars-Sinai Medical Center

Division of Rheumatology

Department of Medicine

Los Angeles, CA, USA

University of California Los Angeles

David Geffen School of Medicine

Los Angeles, CA, USA

Bo Abrahamsen, MD, PhD

University of Southern Denmark

Odense Patient Data Explorative Network

Institute of Clinical Research

Odense, Denmark

Holbæk Hospital

Department of Medicine
Holbæk, Denmark

Inhalt

Foreword   Juliet CompstonPrefaceChapter 1 Osteoporosis: Pathophysiology & Epidemiology          Rebecca J. Moon, Cyrus Cooper, and Nicholas C. HarveyChapter 2 Antiresorptives           R. Graham G. Russell, Maria K. Tsoumpra, Frank H. Ebetino, Michael PazianasChapter 3 Anabolics          Erik Fink EriksenChapter 4 Tools for Assessing Fracture Risk and for Treatment Monitoring          William D. Leslie, Lisa M. Lix, and Suzanne N. MorinChapter 5 Treatment Failure          Elisa Torres del Pliego, Daniel Prieto-Alhambra, and Adolfo Díez-PerezChapter 6 Epidemiology of Atypical Subtrochanteric and Femoral Shaft Fractures          Jeri W. NievesChapter 7 Bisphosphonate-Related Atypical Femoral Fractures and Their Radiographic Features           Joseph C. Giaconi and C. Travis WattersonChapter 8  Factors Contributing to Atypical Femoral Fractures            Adele L. Boskey and Marjolein C. H. van der MeulenChapter 9  Clinical Presentation of Atypical Femur Fractures            Yelena Bogdan and Thomas A. EinhornChapter 10  Effects of Antiresorptive Therapy on Bone Microarchitecture            Joy N. Tsai and Mary L. BouxseinChapter 11  Management of Atypical Femoral Fractures            Joseph M. Lane, Libi Z. Galmer, David S. Wellman, Abigail L. Campbell, Jonathan E. JoChapter 12  Osteonecrosis of the Jaw: Clinico-Pathologic and Radiologic Features            Parish P. Sedghizadeh and Allan C. JonesChapter 13  Epidemiology of Osteonecrosis of the Jaws from Antiresorptive Treatment             Morten SchiødtChapter 14  Management of Osteonecrosis of the Jaw in Patients Receiving Antiresorptive Treatment                 Morten SchiødtChapter 15  Long-Term Efficacy and Safety of Treatments for Osteoporosis             Socrates E. PapapoulosChapter 16  Management of Drug Holidays            Christian Roux and Karine BriotChapter 17  Patients Who Do Not Take Their Osteoporosis Medications:  Can We Help Them Become Compliant?             Deborah T. GoldChapter 18  Fractures and Healing on Antiresorptive Therapy            Eli Kupperman and Susan V. BukataChapter 19 Antiresorptive Therapy and Mortality and Cancer Incidence            Peter VestergaardChapter 20  Other Safety Concerns            Michael R. McClungChapter 21  The Impact of Regulatory and Scientific Organizations Recommendations on Clinical Decision Making            Alexandra Papaioannou, Arnav Agarwal, and Sarah KarampatosChapter 22  Integrated Clinical View on Long-Term Management of  Patients with Osteoporosis             E. Michael LewieckiChapter 23  Conclusions            Stuart L. Silverman and Bo Abrahamsen

Produkt-Details

• Erscheint lt. Verlag: 29.12.2015
• Zusatzinfo: XVI, 338 p. 100 illus., 38 illus. in color.
• Verlagsort: Cham
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete
• Schlagworte: Anabolic therapy • Antiresorptive therapy • Atypical femur fracture • Bisphosphonates • Bone microarchitecture • Drug holiday • Fracture risk assessment • Osteonecrosis of the jaw • Osteoporosis treatment
• ISBN-10: 3-319-23639-3 / 3319236393
• ISBN-13: 978-3-319-23639-1 / 9783319236391