Epigenetics

Mechanisms & Clinical Perspectives

Buch | Hardcover

235 Seiten

2016
Nova Science Publishers Inc (Verlag)
978-1-63484-490-1 (ISBN)

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Epigenetics is a relatively new field of science explaining heritable changes that are not caused by alterations in DNA sequences. Epigenetic modifications are acquired throughout life, and depend on environmental clues such as diet, lifestyle and toxin exposure. It is possible to pass down epigenetic modifications to the next generation of offspring if the modifications occur in sperm or egg cells. Additionally, epigenetic regulations are central to many cellular processes such as imprinting, X chromosome inactivation, DNA damage response, cellular reprogramming and senescence. This book provides an overview for the influence of early life nutrition on the epigenome and the role of epigenetic dysregulations in the pathogenesis of many common diseases.

Preface; Epigenetic Modifications & Developmental Origin of Health & Diseases (DOHaD); Effects of Oxidative Stress on Epigenetic Mechanisms; Epigenetic Modifications & Their Potential Role in Tumorigenesis; Alzheimers Disease: An Insight from Epigenetic Perspective; Epigenetic Mechanisms in Cardiovascular Diseases; Insights from Epigenomics Analysis of Sperm: Sperm Development & Male Infertility; Epigenetics, Inflammation & Inflammatory Related-Diseases: A General Look; A New Molecular Approach to Obesity: Epigenetic Perspective; Index.

Erscheinungsdatum	03.03.2016
Verlagsort	New York
Sprache	englisch
Maße	180 x 260 mm
Gewicht	634 g
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
Themenwelt	Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie
ISBN-10	1-63484-490-4 / 1634844904
ISBN-13	978-1-63484-490-1 / 9781634844901
Zustand	Neuware