Transgenics in Endocrinology

Martin Matzuk, Chester W. Brown, T. Rajendra Kumar (Herausgeber)

Buch | Hardcover

486 Seiten

2001
Humana Press Inc. (Verlag)
978-0-89603-764-9 (ISBN)

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A panel of expert clinical and basic investigators summarize the state-of-the-art in the use of transgenic technology in a broad range of endocrinological applications. Up-to-date and comprehensive, Transgenics in Endocrinology reviews the most recent developments in the analysis of endocrine physiology and its pathologies through mouse models, and provides a host of creative approaches to understand better the complex processes that are characteristic of hormonal systems.

1 Germline Genetic Engineering Techniques in Endocrinology.- 2 The Transgenic Mouse in Studies of Mammalian Sexual Differentiation.- 3 The In Vivo Function of Müllerian-Inhibiting Substance During Mammalian Sexual Development.- 4 Control of Ovarian Function.- 5 Mouse Models to Study the Pituitary-Testis Interplay Leading to Regulated Gene Expression.- 6 Functional Analysis of the Bcl2 Gene Family in Transgenic Mice.- 7 The Role of C-Kit/Kit Ligand Axis in Mammalian Gametogenesis.- 8 Gene Knockout Approaches to Steroidogenesis.- 9 The Progesterone Receptor Knockout Mouse Model: New Insights into Progesterone Action In Vivo.- 10 Knockout and Transgenic Mouse Models that Have Contributed to the Understanding of Normal Mammary Gland Development.- 11 Prolactin and the Prolactin Receptor.- 12 Transgenic Models for Oxytocin and Vasopressin.- 13 Glycoprotein Hormones: Transgenic Mice as Tools to Study Regulation and Function.- 14 Genetic Approaches to the Study of Pituitary Follicle-Stimulating Hormone Regulation.- 15 Transgenic Analysis of the Proopiomelanocortin Neuroendocrine System.- 16 Overexpression and Targeted Disruption of Genes Involved in the Control of Growth, Food Intake, and Obesity.- 17 Insulin and Insulin-Like Growth Factors: Targeted Deletion of the Ligands and Receptors.- 18 Use of Transgenic Animals in Skeleton Biology.- 19 Transgenic Mouse Models of Prostate Cancer.- 20 Neural- and Endocrine-Cell-Specific Immortalization Using Transgenic Approaches.

Erscheint lt. Verlag	15.8.2001
Reihe/Serie	Contemporary Endocrinology
Zusatzinfo	X, 486 p.
Verlagsort	Totowa, NJ
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie
Themenwelt	Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie
ISBN-10	0-89603-764-9 / 0896037649
ISBN-13	978-0-89603-764-9 / 9780896037649
Zustand	Neuware