Jubb, Kennedy & Palmer's Pathology of Domestic Animals: Volume 1 (eBook)

Grant Maxie (Autor)

eBook Download: EPUB

2015 | 6. Auflage
912 Seiten
Elsevier Health Sciences (Verlag)
978-0-7020-6842-3 (ISBN)

Infos

With an emphasis on the disease conditions of dogs, cats, horses, swine, cattle and small ruminants, Jubb, Kennedy, and Palmer's Pathology of Domestic Animals, 6th Edition continues its long tradition of being the most comprehensive reference book on common domestic mammal pathology. Using a body systems approach, veterinary pathology experts provide overviews of general system characteristics, reactions to insult, and disease conditions that are broken down by type of infectious or toxic insult affecting the anatomical subdivisions of each body system. The sixth edition now boasts a new full-color design, including more than 2,000 high-resolution images of normal and abnormal organs, tissues, and cells. Updated content also includes evolved coverage of disease agents such as the Schmallenberg virus, porcine epidemic diarrhea virus, and the porcine deltacoronavirus; plus new information on molecular-based testing, including polymerase chain reaction (PCR) and in-situ hybridization, keep you abreast of the latest diagnostic capabilities.

• Updated content includes new and evolving pathogens and diagnostic techniques.


• Updated bibliographies give readers new entry points into the rapidly expanding literature on each subject.

• NEW! High-resolution color images clearly depict the diagnostic features of hundreds of conditions.


• NEW! Introduction to the Diagnostic Process chapter illustrates the whole animal perspective and details the approaches to systemic, multi-system, and polymicrobial disease.


• NEW! Coverage of camelids is now included in the reference's widened scope of species.


• NEW! Team of 30+ expert contributors offers the latest perspective on the continuum of issues in veterinary pathology.


• NEW! Expanded resources on the companion website include a variety of helpful tools such as full reference lists with entries linked to abstracts in Pub Med and bonus web-only figures.


• NEW! Full-color design improves the accessibility of the text.

Textauszug

Chapter 2

Bones and Joints

Linden E. Craig, Keren E. Dittmer, Keith G. Thompson

DISEASES OF BONES 17

GENERAL CONSIDERATIONS 17

STRUCTURE AND FUNCTION OF BONE TISSUE 17

Cellular elements 17

Bone matrix 19

Matrix mineralization 20

Structural organization of bone tissue 20

Development and anatomy 21

Hormonal regulation of physeal growth 24

Modeling 24

Remodeling 26

Markers of remodeling 27

Blood supply 27

POSTMORTEM EXAMINATION OF THE SKELETON 28

Gross examination 28

Histologic techniques and stains 28

Preparation artifacts in histologic sections 29

Other laboratory techniques 29

RESPONSE TO MECHANICAL FORCES AND INJURY 30

Mechanical forces 30

Growth plate damage 30

Angular limb deformities 31

Periosteal damage 33

Fracture repair 33

Types of fractures 34

Process of fracture repair 34

Complications of fracture repair 35

Stress-related lesions in horses 36

GENETIC AND CONGENITAL DISEASES OF BONE 36

Generalized skeletal dysplasias 37

Chondrodysplasias 37

Chondrodysplasias of cattle 38

Chondrodysplasias of sheep 40

Chondrodysplasias of pigs 42

Chondrodysplasias of horses 42

Chondrodysplasias of dogs 43

Chondrodysplasias of cats 45

Osteogenesis imperfecta 46

Osteopetrosis 50

Congenital hyperostosis 53

Osteochondromatosis 54

Idiopathic multifocal osteopathy 54

Localized skeletal dysplasias 54

Limb dysplasias 54

Skull anomalies 56

Sternum and ribs 56

Pelvis 56

Vertebrae 57

Genetic diseases indirectly affecting the skeleton 57

Lysosomal storage diseases 57

Congenital erythropoietic porphyria 59

NUTRITIONAL AND HORMONAL BONE DISEASES 60

Nutritional imbalances affecting skeletal growth 60

Calcium, phosphorus, and vitamin D deficiency 61

Calcium and phosphorus homeostasis 61

Osteoporosis 63

Rickets and osteomalacia 68

Fibrous osteodystrophy 74

Other mineral imbalances 80

Other vitamin imbalances 82

TOXIC BONE DISEASES 84

Molybdenosis 84

Fluorosis 84

Lead toxicity 86

Vitamin A toxicity 86

Vitamin D toxicity 89

Plant toxicities 90

Other toxicities 91

HYPEROSTOTIC DISEASES 91

Craniomandibular osteopathy 91

Calvarial hyperostosis of Bullmastiffs 92

Hypertrophic osteopathy 92

Canine hepatozoonosis 94

OSTEONECROSIS 94

Morphology and fate of necrotic bone 95

Legg-Calvé-Perthes disease 97

INFLAMMATORY AND INFECTIOUS DISEASES OF BONES 97

Bacterial osteomyelitis 98

Fungal osteomyelitis 103

Viral infections of bones 104

Metaphyseal osteopathy 105

Canine panosteitis 106

TUMORS AND TUMOR-LIKE LESIONS OF BONES 107

Bone-forming tumors 109

Osteoma, ossifying fibroma, and fibrous dysplasia 109

Osteosarcoma 110

Cartilage-forming tumors 116

Chondroma 116

Osteochondroma 116

Multilobular tumor of bone 117

Chondrosarcoma 118

Fibrous tumors of bones 121

Vascular tumors of bones 122

Other primary bone tumors  122

Secondary tumors of bones 124

Tumor-like lesions of bones 125

DISEASES OF JOINTS 128

GENERAL CONSIDERATIONS 128

Fibrous joints 128

Cartilaginous joints 128

Synovial joints 129

Response of articular cartilage to injury 131

DEVELOPMENTAL DISEASES OF JOINTS 132

Osteochondrosis 132

Hip dysplasia 135

Cervical vertebral malformation-malarticulation 136

Luxations and subluxations 137

DEGENERATIVE DISEASES OF JOINTS 137

Synovial joints 137

Cartilaginous joints 143

Spondylosis 145

INFLAMMATORY DISEASES OF JOINTS 146

Fibrinous arthritis 146

Purulent (suppurative) arthritis 147

Infectious arthritis 148

Bacterial arthritis 148

Viral arthritis 154

Fungal arthritis 154

Protozoal arthritis 155

Miscellaneous inflammatory lesions of joint structures 155

Bursitis 155

Diskospondylitis 156

Calcium crystal–associated arthropathy (pseudogout) 156

Immune-mediated polyarthritis 157

TUMORS AND TUMOR-LIKE LESIONS OF JOINTS 159

Malignant tumors 159

Synovial cell sarcoma 159

Histiocytic sarcoma 159

Other sarcomas 160

Benign tumors 160

Synovial myxoma 160

Non-neoplastic lesions 162

Synovial chondromatosis 162

Synovial cysts 162

Synovial pad proliferation 163

Acknowledgments

The update of the chapter is based on previous editions by Dr. Ken Jubb and Dr. Nigel Palmer. It is an honor to follow in their footsteps. We are grateful to the many pathologists who contributed illustrations to this chapter.

Diseases of Bones

General Considerations

Bone is a highly specialized connective tissue, its properties depending largely on the unique nature of its extracellular matrix. In addition to providing mechanical support and protecting key organ systems from traumatic injury, bone is intimately involved in the homeostasis of calcium, an essential cation in a wide range of...

Produkt-Details

• Erscheint lt. Verlag: 16.8.2015
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie
• Themenwelt: Veterinärmedizin ► Vorklinik
• Themenwelt: Veterinärmedizin ► Klinische Fächer ► Pathologie
• ISBN-10: 0-7020-6842-X / 070206842X
• ISBN-13: 978-0-7020-6842-3 / 9780702068423