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Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management

Aamir Ahmad, Shirish M. Gadgeel (Herausgeber)

Buch | Hardcover

X, 231 Seiten

2016 | 1st ed. 2016
Springer International Publishing (Verlag)
978-3-319-24931-5 (ISBN)

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This, the second of two volumes on personalized medicine in lung cancer, touches upon the recent progress in targeted drug development based on genomics; emerging biomarkers and therapeutic targets such as EMT, cancer stem cells, and the tumor microenvironment; current personalized clinical management and radiation therapy for lung cancers; and the promise of epigenetics and next-generation sequencing for the advancements towards personalized therapy of lung cancer patients. With chapters on state-of-the-art therapies and technologies written by leading experts working to develop novel companion diagnosis tools for the personalized treatment of lung cancer patients, this volume brings readers up-to-date by presenting the current knowledge on the efforts to make personalized management of lung cancer patients a reality.

Aamir Ahmad, PhD, is a Scientist at the Wayne State University School of Medicine Department of Pathology and the Karmanos Cancer Institute, with over 100 published scientific articles in peer-reviewed journals and many book chapters. He has been a member of leading cancer organizations such as American Association for Cancer Research (AACR, Philadelphia, USA) and International Union against Cancer (UICC, Geneva, Switzerland). In addition to serving as a reviewer for a number of peer-reviewed scientific journals, he is currently a Section Editor for the journal PLoS ONE responsible for policy drafts for the journal and identification and management of special issues. In addition to the current volume, Dr. Ahmad has worked with Springer to edit two more volumes, Breast Cancer Metastasis and Drug Resistance and Lung Cancer and Personalized Medicine: Current Knowledge and Therapies.Shirish M. Gadgeel is a Professor in the Department of Oncology at Karmanos Cancer Institute/Wayne State University in Detroit. He is also the co-leader of the Molecular Therapeutics Program of Karmanos Cancer Institute and the Leader of the Multidisciplinary Thoracic Oncology team. He is a member of several professional societies, including the American Society of Clinical Oncology and the International Association for the Study of Lung Cancer. He currently serves on the Editorial Board of the journals Cancer and Clinical Lung Cancer. Dr. Gadgeel has been and is a Principal Investigator of several trials focused on the treatment of Lung Cancer. He has over 80 peer reviewed publications.

1 Lung Cancer Genomics in the Era of Accelerated Targeted Drug Development.-2 Emerging Biomarkers in Personalized Therapy of Lung Cancer.-3 Epithelial mesenchymal transition in aggressive lung cancers.-4 The Role of Cancer Stem Cells in Recurrent and Drug-Resistant Lung Cancer.-5 The microenvironment of lung cancer and therapeutic implications.-6 Epigenetics in Personalized Management of Lung Cancers.-7 Next-Generation Sequencing and Applications to the Diagnosis and Treatment of Lung Cancer.-8 Nanomedicine for Treatment of Lung Cancer.-9 Personalized Therapy of Small Cell Lung Cancer.-10 Personalized Radiation Therapy for Lung Cancer.-11 Current Clinical Management in the era of personalized therapy.-11 Personalized Therapy of Non-Small Cell Lung Cancer.

Erscheinungsdatum	08.10.2016
Reihe/Serie	Advances in Experimental Medicine and Biology
Zusatzinfo	X, 231 p. 22 illus., 21 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
Themenwelt	Medizin / Pharmazie ► Studium
Schlagworte	Biomedical and Life Sciences • Cancer Research • genomics • Lung Cancer • radiation therapy • small cell lung cancer • Stem Cells • Therapeutic Implications
ISBN-10	3-319-24931-2 / 3319249312
ISBN-13	978-3-319-24931-5 / 9783319249315
Zustand	Neuware