Genistein & Daidzein

Food Sources, Biological Activity & Health Benefits

Buch | Hardcover

193 Seiten

2015
Nova Science Publishers Inc (Verlag)
978-1-63483-194-9 (ISBN)

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Soybeans are greatly used in many foods, such as tofu, soy milk and yogurt, and it plays an important role as a functional food in the health and prevention of various diseases. Soybeans contain rich isoflavones including genistein, daidzein and glycitein, and both genistein and daidzein occur at higher concentrations. Isoflavones are structurally and functionally similar to 17ssestradiol. Isoflavones are found to bind to estrogen receptors and the peroxisome proliferator-activated receptor (PPAR) family and aryl hydrocarbon receptors. Moreover, isoflavones affect activity of tyrosine kinases, histones, transcription factors, adenosine mono phosphate pathways, RNA expression and other intracellular regulators. Thus, isoflavones play a multifunctional role in cell regulation. This book focuses on recent advances in the food sources, biological activity and health benefits of genistein and daizen.

Masayoshi Yamaguchi, Ph.D., IOM, FAOE, DDG, DG, is Adjunct Professor, Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA (2013 - ). Dr. Yamaguchi is engaged in the fields of endocrinology and cell signaling since 1971, and these researches are developed in the aspect of biochemistry, molecular biology, endocrinology, metabolism, nutrition, pharmacology, and toxicology. Dr Yamaguchi has an interesting for cell signaling mechanism, bone biology, nutritional factor and osteoporosis prevention, diabetes and diabetic osteoporosis, cancer biology, and cancer cell bone metastasis. Dr. Yamaguchi discovered two novel proteins and genes; cell signaling suppressor protein (named regucalcin; 1978) and transcriptional factor RGPR-p117 (regucalcin gene promoter region-related protein; 2001). Dr Yamaguchi generated regucalcin transgenic rats, which were registered as international patents including USA, EU and Japan, and this animal was found to induce osteoporosis and hyperlipidemia. Moreover, Dr. Yamaguchi proposed the potential role of regucalcin as a key suppressor protein in carcinogenesis. Thus far, Dr Yamaguchi published over 550 English articles to professional journals with peer-review, and registered over 20 national and international patents.

Preface; Effects of Genistein & Daidzein in Female Reproductive Tract; Daidzein & Genistein: Endothelial Action of an Aglycone-Rich Extract; Role of Genistein in Bone Homeostasis: Prevention of Osteoporosis; Contemporary Clinical Effects of Phytoestrogens Administration; Bone Formation: Roles of Genistein & Daidzein; Index.

Verlagsort	New York
Sprache	englisch
Maße	180 x 260 mm
Gewicht	414 g
Themenwelt	Medizin / Pharmazie ► Gesundheitsfachberufe ► Diätassistenz / Ernährungsberatung
ISBN-10	1-63483-194-2 / 1634831942
ISBN-13	978-1-63483-194-9 / 9781634831949
Zustand	Neuware