Are Chronic Degenerative Diseases Part of the Ageing Process?

Insights from Comparative Biology

Buch | Softcover

312 Seiten

2015
Nova Science Publishers Inc (Verlag)
978-1-63483-024-9 (ISBN)

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Most of the DNA in the human genome does not encode proteins but is involved in regulatory functions. In addition, the human genome is characterized by an extensive array of structural DNA variants arising from de novo mutations plus accumulated structural variants transmitted through an individual's lineage. The result is that each person has a unique genome which is expressed as that person's unique phenotype. Ageing can be understood on both the species and individual level. Each species has a programmed ageing and mortality pattern, but within those broad species-specific boundaries there is considerable individual variation. At the individual level, ageing reflects the integrated effects of that individual's unique mix of DNA structural variants, unique experience-specific epigenetic marks and imperfectly repaired genomic and cellular damage. This book examines human "chronic degenerative" diseases which are not diseases, but rather variations of the ageing process across individuals.

Introduction; Background; Atherosclerotic Vascular Disease; Hypertension; Diabetes Mellitus (Type 2); Dementia; Conclusions; Bibliography; Index.

Erscheint lt. Verlag	1.9.2015
Verlagsort	New York
Sprache	englisch
Maße	180 x 260 mm
Gewicht	444 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Geriatrie
ISBN-10	1-63483-024-5 / 1634830245
ISBN-13	978-1-63483-024-9 / 9781634830249
Zustand	Neuware