Sphingomyelin & Ceramides

Occurrence, Biosynthesis & Role in Disease

Buch | Softcover

75 Seiten

2015
Nova Science Publishers Inc (Verlag)
978-1-63482-553-5 (ISBN)

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Sphingolipids are involved in a wide range of physiological and pathological processes none only as signalling molecules but also as key structural components regulating the lateral organisation of cellular membranes. In this book, exciting new approaches that open a window to further characterise sphingolipid-enriched domains in cell membranes during both physiological and pathological processes are reviewed. Furthermore, sphingolipids (SLs) are especially important in the central nervous system (CNS) where they are a necessary structural component of membranes of brain cells or signalling molecules. Ceramides are the core constituent of most sphingolipids. The authors review the possible sources of ceramides in the central nervous system (CNS) and present information about recent preclinical clinical trials of therapies targeting the ceramide pathway in the brain. Data about significant alteration in levels of ceramides in brain cells during the development of different neurodegenerative disease are also discussed, such as in with Alzheimer's disease, Parkinson's disease multiple sclerosis, cerebral ischemia, Gaucher's and Farber's disease.

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Erscheint lt. Verlag	1.6.2015
Verlagsort	New York
Sprache	englisch
Maße	155 x 230 mm
Gewicht	172 g
Themenwelt	Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Zoologie
ISBN-10	1-63482-553-5 / 1634825535
ISBN-13	978-1-63482-553-5 / 9781634825535
Zustand	Neuware