Anabolic Steroids (eBook)

H.-L. Kruskemper (Autor)

eBook Download: PDF

2013 | 1. Auflage
246 Seiten
Elsevier Science (Verlag)
978-1-4832-6504-9 (ISBN)

Infos

Anabolic Steroids attempts to trace the development of anabolic steroids in the chemical, experimental biological, and clinical disciplines, and presents a precise outline of the current state of substantiated knowledge. This book deals with anabolic steroids derived from natural androgens and characterized by their stimulatory action on the biosynthesis of tissue protein and by their simultaneous low androgenicity. The biochemical part is a review of substantiated and current knowledge based largely on experimental results with animals, while the clinical part attempts to bring out the pathophysiological rationale of therapy with anabolic steroids, again based on experimental data. The book begins with a discussion of the nomenclature and chemistry of anabolic steroids. This is followed by separate chapters on the metabolism, activities, and mechanism of action of anabolic steroids; clinical application of anabolic steroids, side effects, and test procedures.

Inhalt

Front Cover 1
Anabolic Steroids 4
Copyright Page 5
Table of Contents 8
Preface to First German Edition 6
Chapter 1. Introduction 12
Text 12
Chapter 2. Nomenclature and Chemistry of Anabolic Steroids 14
Text 14
Chapter 3. Metabolism of Anabolic Steroids 32
Text 32
Chapter 4. Activities of Anabolic Steroids 42
A. Myotropic Activity and the Myotropic-Androgenic Index of Anabolic Steroids 42
B. Retention of Nitrogen, Potassium, Phosphorus, and Calcium Weight Gain
C. Creatine Metabolism 69
D. Carbohydrate Metabolism 72
E. Lipid Metabolism 74
F. Basal Metabolism Tissue Metabolism
G. Water and Electrolyte Metabolism 77
H. Connective Tissue Skeleton
I. Thymus 83
J. Liver 84
K. Kidney 86
L. Anticatabolic Activity of Anabolic Steroids 88
M. Normal and Pathologic Growth 97
N. Hormonal Side Effects of Anabolic Steroids 98
Chapter 5. Mechanism of Action of Anabolic Steroids 116
Text 116
Chapter 6. Clinical Application of Anabolic Steroids 130
A. Indications for Therapy with Anabolic Steroids 134
B. Contraindications 176
Chapter 7. Side Effects of Anabolic Steroids 178
Text 178
Chapter 8. Test Procedures for Anabolic Steroids 196
A. The Myotropic-Androgenic Index (38) 196
B. Demonstration of Nitrogen-Retaining (Anabolic) Activity 197
C. Protective Effect of Anabolic Steroids 201
D. Antigonadotropic Activity 203
E. Extrogenic, Antiestrogenic, and Gestagenic Activity of Anabolic Steroids 204
Appendix 206
Bibliography 216
Subject Index 236

Produkt-Details

• Erscheint lt. Verlag: 22.10.2013
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie
• ISBN-10: 1-4832-6504-8 / 1483265048
• ISBN-13: 978-1-4832-6504-9 / 9781483265049