Antibiotics (eBook)

Origin, Nature and Properties

Tadeusz Korzybski, Zuzanna Kowszyk-Gindifer, Wlodzimierz Kurylowicz (Autoren)

eBook Download: PDF

2013 | 1. Auflage
536 Seiten
Elsevier Science (Verlag)
978-1-4832-2304-9 (ISBN)

Infos

Antibiotics; Origin, Nature and Properties, Volume II focuses on the principles of the classification of antibiotic substances. This volume is divided into four main topics-antibiotics produced by Fungi imperfecti, antibiotics produced by fungi belonging to the basidiomycetes and ascomycetes, antibiotics produced by lichens and algae, and antibiotics from higher plants. The antibiotics covered in this book include penicillin, viridicatin, cyclopaldic acid, cephalosporin P, bongkrek acid, chlamydosporine, and flammulin. The diploicin, chlorellin, chlorophorin, ethyl gallate, anacardic acid, and echinacosid are also described. Other antibiotics include the tuberosine, antifungal substance from field corn, fulvoplumerin, plumericin, and chinoc acid. This publication is recommended for pharmacists and specialists interested in the classification of antibiotics.

Inhalt

Front Cover 1
Antibiotics Origin, Nature and Properties 4
Copyright Page 5
Table of Contents 6
Contents Of Volume I 12
PART III: ANTIBIOTICS PRODUCED BY FUNGI IMPERFECTI 
21 
Chapter 1. A. ANTIBIOTICS ISOLATED FROM THE GENUS PENICILLIUM 21
P E N I C I L L I N 21
REFERENCES 40
6 - AMINOPENICILLANIC ACID 41
SEMISYNTHETIC PENICILLINS 45
6-BENZYLSULPHONAMIDOPENICILLANIC ACID 50
2,6-DIMETHOXYPHENYL P E N I C I L L I N 51
2-METHOXY-l-NAPHTHAMIDOPENICILLIN AND 2-..... Y - l -N AP HTH AM ID OPENICILLIN 53
a-AMINOBENZYL PENICILLIN 54
3,4-DICHLORO-a-METHOXYBENZYL PENICILLIN 55
a-PHENOXYETHYL PENICILLIN 56
a-PH . . OXY PROPYL PENICILLINf 58
PHENOXYBENZYL PENICILLIN 59
5-METHYL-3-0-CHLOROPHENYL-4-I SOXAZOLYL PENICILLIN 61
QUINACILLIN 63
REFERENCES 64
PENICILLIC ACID 68
REFERENCES 72
FUMARYL-DL-ALANINE 72
REFERENCE 73
GENTISYL ALCOHOL 73
REFERENCES 74
CYCLOPALDIC ACID 74
REFERENCES 75
GLADIOLIC ACID 75
REFERENCES 78
MYCOPHENOLIC ACID 78
REFERENCES 81
BREFELDINS A AND . 82
REFERENCES 84
HADACIDIN 84
REFERENCES 85
VARIOTIN 85
REFERENCES 88
SPINULOSIN, SYN. 6-HYDROXYFUMIGATIN 88
REFERENCES 91
PHENICIN 91
PUBERULIC AND PUBERULONIC ACID 92
STIPITATIC ACID 94
KOJIC ACID 95
P A T U L I N , SYN. CLAVACIN, CLAVATIN, C L A V I F O R M I N ,EXPANSIN, PENICIDIN 98
CITRININ, SYN. NOTALIN 105
GRISEOFULVIN, SYN. "CURLING FACTOR", FULCIN, GRISOVIN,GRIFULVIN, FULVICIN, LIKUDEN 110
MYCELIANAMIDE 123
TARDIN 125
FREQUENTIN 127
HERQUEIN 129
FREQUENTIC ACID, SYN. CITROMYCETIN 129
XANTHOCILLIN 131
VIRIDICATIN 132
E S T I N AND NORDIN 133
CANESCIN 134
RUGULOSIN 135
NOTATIN, SYN. P E N I C I L L I N A, P E N I C I L L I N B, PENATIN,E. COLI FACTOR, CORYLOPHYLIN, P. L. FACTOR 136
CYANEIN 141
HELENINE 142
ANTIBIOTIC M5-8450 144
CARNEOLUTESCIN 144
PULVILLORIC ACID 145
WORTMANNIN 145
MYCOINS 146
NOTALYSINE 147
ANTIBIOTIC X 2 9 C 147
TRICHOCIDIN 147
ALBIDIN 148
Chapter 2. B. ANTIBIOTICS ISOLATED FROM THE GENUSASPERGILLUS (FUNGI IMPERFECTI) 148
FUMIGATIN 148
MELLEIN 150
ASPERGILLIC ACID 151
HYDROXYASPERGILLIC ACID 155
NEOHYDROXYASPERGILLIC ACID 158
FLAVIPIN 160
NIDULIN, USTIN, S Y N . NORNIDULIN, AND OTHER CHLORINECONTAININGMETABOLIC PRODUCTS OF ASPERGILLUS USTUS 162
GEODIN 164
TRYPACIDIN 166
QUADRILINEATIN 168
TERREIC ACID 169
FUMAGILLIN, S Y N . PHAGOPEDIN SIGMA, FUGILLIN, FUMIDIL 170
HELVOLIC ACID 173
AVENACIOLIDE 176
CANDIDULIN 177
ASPERGILLIN 179
AURANTIDIN 180
GIGANTINE 180
HUMICOLIN 180
MYCOCIDIN 181
PROLIFERIN AND VARIECOLIN 182
ORYZACIDIN 182
WELUTININ 182
STERIGMATOCYSTIN 183
Chapter 3. C. ANTIBIOTICS ISOLATED FROM THE GENUS FUSARIUM(FUNGI IMPERFECT!) 185
LYCOMARASMIN 185
ENNIATINS 187
LATERITIIN, AVENACEIN, FRUCTIGENIN, SAMBUCININ 191
JAVANICIN, OXYJAVANICIN, S Y N . FUSARUBIN 194
FUSARINIC ACID 197
BOSTRYCOIDIN 198
POINE 200
CHLAMYDO SPORINE 200
FUSANIN 200
Chapter 4. D. ANTIBIOTICS ISOLATED FROM GLIOCLADIUM, CEPHALOSPORIUM,ALTERNARÍA, TRICHOTHECIUM AND OTHER GENERA 201
AURANTIOGLIOCLADIN, GLIOROSEIN AND RUBROGLIOCLADIN 201
CEPHALOSPORIN N, SYNNEMATIN . 202
CEPHALOSPORIN C 204
SYNNEM ATINS 210
GLIOTOXIN AND GLIOTOXIN MONOACETATE 214
CORDYCEPIN 219
AUXINS 221
CEPHALOSPORIN . 222
CEPHALOSPORIN R 225
CERULENIN 226
VERRUCARIN AND RORIDIN 226
FUCIDIN 235
ALTERNARIC ACID 238
ANTIBIOTIC OF MONOSPORIUM BONORDEN, S Y N . MONORDEN 239
TRICHOTHECIN 242
TRICHODERMIN 244
ROSEIN 245
GLUTINOSIN 247
ZIZANIN 249
SICCANIN 250
PYRENOPHORIN 251
OPHIOBOLIN 252
BONGKREK ACID 252
FUSCIN 252
RAMYCIN 254
ANTIBIOTICS OF RHODOTORULA 256
MALUCIDIN 257
M Y C E L I N 258
ACHORICINS 258
ANTIBIOTIC SUBSTANCES FROM MEDUSOMYCES GISEWII 259
FULIGONIN 259
ANTIBIOTIC FROM CERCOSPORA BETICOLA 260
PART IV: ANTIBIOTICS PRODUCED BY FUNGI BELONGINGTO THE BASIDIOMYCETES AND ASCOMYCETES 261
Chapter 5. DIATRETYNE 261
Chapter 6. GRIFOLIN 261
Chapter 7. NEMOTIN , NEMOTINICACID , NEMOTINA 262
Chapter 8. QUADRIFIDIN 263
Chapter 9. AGROCYBIN 264
Chapter 10. DROSOPHILIN A 264
Chapter 11. SPARASSOL 265
Chapter 12. 6-METHYL-l,4-NAPHTHOQUINONE 265
Chapter 13. LACTARIOVIOLIN 266
Chapter 14. NUDIC ACIDS 267
Chapter 15. HIRSUTIC ACID 268
Chapter 16. ILLUDINS . AND S 269
Chapter 17. TRICHOTHECIN-LIKE ANTIBIOTIC . 270
Chapter 18. THERMOPHYLLIN 271
Chapter 19. USTILAGIC ACID 271
Chapter 20. USTIZEANINE A AND . 272
Chapter 21. MARASMIC ACID 272
Chapter 22. OREGONENSIN 274
Chapter 23. PLEUROTIN 275
Chapter 24. UNGULINIC ACID 275
Chapter 25. POLYPORENIC ACID 276
Chapter 26. BACCATINE 277
Chapter 27. CHAETOMIN 277
Chapter 28. ANTIBIOTIC FROM LACTARIA RUFA 279
Chapter 29. TUMOUR INHIBITORS IN BOLETUS EDULIS 280
Chapter 30. FLAMMULIN 281
Chapter 31. CALVACIN 282
Chapter 32. FOMECIN A 283
Chapter 33. PLEUROMUTILIN 284
Chapter 34. LENZITIN 284
Chapter 35. POLYSTICTIN 285
Chapter 36. INOLOMIN 285
Chapter 37. NEBULARINE 286
Chapter 38. RAMEALIN 287
Chapter 39. BIFORMIN AND BIFORMINIC ACID 287
Chapter 40. DESTRUIN 289
Chapter 41. POLYPORIN 289
Chapter 42. CLITOCYBINE 290
Chapter 43. PSALLIOTIN 291
Chapter 44. PICACIC ACID 291
Chapter 45. DENDRODOCHINE 292
Chapter 46. ANTIBIOTIC FROM CONIOPHORA CEREBELLA 292
Chapter 46. OBTUSIN, CORTICIN, IRPEXIN, GRISIC ACID, PLEURIN 293
PART V: ANTIBIOTICS PRODUCED BY LICHENS AND ALGAE 294
Chapter 47. COMPOUNDS WITH ANTIBIOTIC ACTIVITY OBTAINEDFROM LICHENS 294
Chapter 48. USNIC ACID 304
Chapter 49. DYDIMIC ACID 308
Chapter 50. DIPLOICIN 309
Chapter 51. ENDOCROCIN 310
Chapter 52. POLYPORIC ACID 310
Chapter 53. LECANORIN A 311
Chapter 54. CHLORELLIN 311
Chapter 55. ANTIBACTERIAL SUBSTANCES FROM TROPICAL MARINE ALGAE 312
PART VI: ANTIBIOTICS FROM HIGHER PLANTS 313
Chapter 56. ALLICIN, ALLISTATIN 313
Chapter 57. RAPHANIN AND SULFORAPHEN 316
Chapter 58. CHEIROLIN 317
Chapter 59. CANAVANINE 319
Chapter 60. LUPULON AND HUMULON 319
Chapter 61. ALAMANDIN 323
Chapter 62. CHAULMOOGRIC AND HYDNOCARPIC ACIDS 324
Chapter 63. BISABOLOL 324
Chapter 64. ANTIBIOTIC FROM ARISTOLOCHIA SP. 325
Chapter 65. ETHYLGÁLLATE 327
Chapter 66. CAFFEIC ACID 329
Chapter 67. ANACARDIC ACID 329
Chapter 68. TRICHOCARPIN 330
Chapter 69. PINOSYLVINE AND I T S MONOMETHYL ETHER 331
Chapter 70. TETRAHYDROXYSTILBENE 332
Chapter 71. NORDIHYDROGUAIARETIC ACID 333
Chapter 72. CURCUMIN 334
Chapter 73. PHLORETIN 335
Chapter 74. CHLOROPHORIN 335
Chapter 75. MORELLIN 336
Chapter 76. GUTTIFERINS 338
Chapter 77. 2-METHOXY-l,4-NAPHTHOQUINONE 339
Chapter 78. JUGLONE 340
Chapter 79. PLUMBAGIN 341
Chapter 78. PRISTIMERIN 341
Chapter 79. RHEIN, S Y N . CASSIC ACID 343
Chapter 80. THUJAPLICINS 344
Chapter 81. NOOTKATIN 346
Chapter 82. PARASORBIC ACID 347
Chapter 83. ANEMONIN AND PROTOANEMONIN 348
Chapter 84. DICUMAROL 350
Chapter 85. PHASEOLLIN 352
Chapter 86. SESAMIN , ASARININ , EUDES MIN , PINORESINOL ,SYRINGARESINOL 353
Chapter 87. QUERCETIN AND DATISCETIN 354
Chapter 88. CHLOROPHYLL 355
Chapter 89. ALKALOIDS WITH ANTIBIOTIC ACTIVITY 355
Chapter 90. BERBERINE AND UMBELLATINE 357
Chapter 91. V I N A L I N E 358
Chapter 92. D E M I S S I N E 358
Chapter 93. ECHINACOSID 360
Chapter 94. HEDERIN 360
Chapter 95. CASSILISIN 360
Chapter 96.TOMATINE, S Y N . LICOPERSICINE 361
Chapter 96. SOLANOCAPSINE 363
Chapter 97. TUBEROSINE 363
Chapter 98. ANTIPROTOZOAL SUBSTANCE FROM POTATO 365
Chapter 99. ANTIFUNGAL SUBSTANCE FROM F I E L D CORN 365
Chapter 100. ANTIBACTERIAL PRINCIPLE OF WITHANIA SOMNÍFERA 366
Chapter 101. WITHAFERIN 368
Chapter 102. CHAKSINE 369
Chapter 103. ANTIBIOTIC PRINCIPLE OF MENISPERMUM CANADENSE 369
Chapter 104. BARBALOIN 369
Chapter 105. ASIATICOSIDE AND OXYASIATICOSIDE 370
Chapter 106. VEGETABLE TANNINS 371
Chapter 107. ANTIBIOTIC FROM INULA SPIRAEIFOLIA 371
Chapter 108. ANTIBIOTIC SUBSTANCE FROM MICONIA SP. {MELASTOMACEAE) 371
Chapter 109. ANTIBIOTIC FROM SPIRAEA ARUNCUS 372
Chapter 110. ANTIBIOTICS FROM FRAGARIA GENUS 373
Chapter 111. XANTHATIN 373
Chapter 112. CREPIN 373
Chapter 113. PLUMERICIN 374
Chapter 114. CHINOC ACID 376
Chapter 115. ANTIBIOTICS FROM ARCTIUM MINUS ANDONOPORDON TAURICUM 376
Chapter 116. ANTIBIOTIC FROM CENTAUREA MACULOSA 376
Chapter 117. ANTIBIOTIC FROM LAPSANA COMMUNIS 377
Chapter 118. PODOPHYLLOTOXIN 377
Chapter 119. IMANINS AND NOVOIMANIN 379
Chapter 120. SECALONIC AND CHRYSERGIC ACID 380
Chapter 121. ANTIBIOTIC FROM ASARUM CANADENSE 380
Chapter 122. ANTIFUNGAL SUBSTANCE FROM THE T I S S U E S OF VICIA FABA 381
Chapter 123. GARLICIN 382
Chapter 124. ANTITUBERCULAR SUBSTANCES FROM ALLIUM SP 382
Chapter 125. CHAMIC ACID 383
Chapter 126. FULVOPLUMERIN 383
Chapter 127. PUROTHIONIN 384
Chapter 128. CANAVALIN 385
Chapter 129. PHYTONCIDES 386
Chapter 130. ANTIBIOTIC FROM COCHLEARIA ARMORACIA 388
Chapter 131. ANTIBIOTICS FROM GRAMINEAE 389
Chapter 132. ANTIBIOTIC FROM AUCUBA JAPÓNICA 389
Chapter 133. ANTIBIOTIC FROM ZANTHOXYLUM RHETSA 389
Chapter 134. CONSATIN-2 390
Chapter 135. ANTIBIOTIC FACTOR FROM ADHATODA VASICA 390
Chapter 136. A NT I TUBERCULAR SUBSTANCE FROM OCCIUM SANCTUM 391
Chapter 137. A NT I TUBERCULAR SUBSTANCES FROM THE LEAVES OFPIPER BETLE AND OTHER PLANTS 391
Chapter 138. ANTIBIOTIC COMPOUND FROM GINGKO BILOBA 391
Chapter 139. ANTIBIOTIC FROM TROPAEOLUM MAIUS 392
Chapter 140. ANTIBIOTICS FROM WOODS OF BRAZILIAN ORIGIN 392
Chapter 141. DALBERGION I AND DALBERGION II 394
Chapter 142. LAPACHOL AND XYLOIDONE 396
Chapter 143. BIFLORIN 398
Chapter 144. URENSIN 401
Chapter 145. SELOVICIN 402
Chapter 146. ANTIFUNGAL SUBSTANCE FROM TABERNAEMONTANA 402
Chapter 147. ANTIBIOTIC FROM TANACETUM BALSAMITA L. 403
Chapter 148. FUNGISTATIC SUBSTANCES FROM LEAF EXUDATES 403
Chapter 149. ERIODIN 404
Chapter 150. ODORIN 404
Chapter 151. PTERIGOSPERMIN 404
Chapter 152. ANTIBACTERIAL PROPERTIES OF ALPINIA GALANGAAND ACORUS CALAMUS 405
Chapter 153. PUCHIIN 406
Chapter 154. RAPINE 406
Chapter 156. SIMAROUBIDIN 407
Chapter 157. SPIROCHIN 407
Chapter 158. TRILOBIN 408
Chapter 159. HOLOTHURIN 408
Chapter 160. ANTIBIOTIC FROM COMMON RAGWEED 408
Chapter 161. ANTIBIOTIC-LIKE SUBSTANCE IN FERMENTED FEEDSAND IN RUMEN FLUID 409
PART V I I: ANTIBIOTICS FROM ANIMAL SOURCES 410
Chapter 162. ANSTIPIN AND EKSTRAZIN 410
Chapter 163. BASIC PEPTIDE FROM CALF THYMUS 411
Chapter 164. SUBSTANCE . 412
Chapter 165. EKMOLIN 413
Chapter 166. HAEM PIGMENTS 416
Chapter 167. SPERMINE 416
Chapter 168. ANTIBACTERIAL SUBSTANCE FROM "CASTOREUM" 417
Chapter 169. ERYTHRIN* 417
Chapter 170. HELICIDIN 418
Chapter 171. ANTIBIOTIC FROM BEROÉ CUCUMIS FABR. 418
Chapter 172. INSECTICIN 419
Chapter 173. ANTIBACTERIAL FACTORS IN PEPTONES 419
Chapter 174. ANTIBIOTIC SUBSTANCE FROM PROTEIN HYDROLYSATES 420
Chapter 175. IRYDOMYRMECIN 420
Chapter 176. ANTIBIOTIC FROM PHORMIA TERRAE NOVAE LARVAE 420
Chapter 177. CRUCIN 421
INDEX OF AUTHORS 422
INDEX OF SUBJECTS 484
INDEX OF ANTIBIOTICS PRODUCERS 512

Produkt-Details

• Erscheint lt. Verlag: 3.9.2013
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie
• ISBN-10: 1-4832-2304-3 / 1483223043
• ISBN-13: 978-1-4832-2304-9 / 9781483223049