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Risk Factors for Cerebrovascular Disease and Stroke -

Risk Factors for Cerebrovascular Disease and Stroke

Buch | Hardcover
488 Seiten
2016
Oxford University Press Inc (Verlag)
978-0-19-989584-7 (ISBN)
CHF 149,95 inkl. MwSt
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This book, by leading stroke researchers from Europe and North America, describes environmental and genetic risk factors for cerebrovascular disease. The section on genetics is exceptionally detailed and contemporaneous.
Risk Factors for Cerebrovascular Disease and Stroke address the relationship of a wide variety of vascular risk factors in the spectrum of cerebrovascular diseases. An international group of professionals the forefront of research and education, provide their expertise about environmental and genetic determinants for cerebrovascular disease and stroke. The authors aim to provide information on developments of genetic, environmental and lifestyle-related risk factors of various subtypes of stroke, and MRI-markers of cerebrovascular disease.

One in 2 men, and 1 in 3 women after the age of 40, will develop a stroke in their lifetime. The burden of cerebrovascular disease extends far beyond that of acute clinical events such as stroke, with "covert " vascular injury on brain MRI being highly prevalent in older community-dwelling persons. Therefore, improving our understanding of the risk factors for stroke and cerebrovascular disease is of paramount importance for improving prevention strategies. Secular trends in stroke epidemiology, risk factors, and intermediate markers (including carotid ultrasound, brain MRI and circulating biomarkers) are presented. Cutting edge information on genetic, environmental and lifestyle-related risk factors of various subtypes of stroke and MRI-markers of cerebrovascular diseases are displayed. This important book is an essential reference to physicians interested in more effective primary prevention of stroke.

Sudha Seshadri, MD Department of Neurology Boston University School of Medicine Investigator, The Framingham Heart Study Boston, MA Stéphanie Debette, MD, PhD Department of Neurology and Epidemiology Paris Diderot University Paris, France

I. Introduction ; 1. Epidemiology of stroke: incidence and prevalence, description of types and subtypes and their relative frequency, definition of risk factors ; II. Genetic risk factors ; 2. Introduction to Genetic risk factors for cerebrovascular disease ; 3. Monogenic forms of stroke and cerebrovascular disease ; 4. Heritability of stroke ; 5. Genetic determinants of ischemic stroke discovered through GWAS ; 6. Genetic risk factors of intracerebral haemorrhage ; 7. Relevance in stroke of genes associated with cardiovascular disease and risk factors/ ; 8. Genetics of Stroke associated with cervical artery dissections ; 9. Genetics of cerebral venous thrombosis ; 10. Genetic risk factors for brain MRI markers of cerebrovascular disease ; III. Environmental risk factors ; 11. Overview of Environmental Risk Factors for Stroke ; 12. Hypertension: the major risk factor for stroke ; 13. Dyslipidemia and Risk of Stroke ; 14. Metabolic risk factors: DM, obesity, metabolic syndrome ; 15. Lifestyle factors and Risk of Stroke: smoking, alcohol, diet, physical activity, sleep ; 16. Risk factors specific to young adults ; 17. Sex-Specific Risk factors for Stroke in Women ; 18. Migraine and Risk of Stroke and Cerebrovascular Disease ; 19. Ethnic, Racial and Geographic Variations in Stroke Risk and Risk Factors ; IV. Integrative approach ; 20. Intermediate markers: Carotid Atherosclerosis ; 21. MRI-based Markers of Cerebrovascular Disease and the Risk of Stroke ; 22. Circulating Biomarkers for Stroke ; 23. Secular trends in Stroke Risk and Risk factors for Stroke

Erscheint lt. Verlag 21.4.2016
Verlagsort New York
Sprache englisch
Maße 236 x 160 mm
Gewicht 816 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Arbeits- / Sozial- / Umweltmedizin
Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Studium 2. Studienabschnitt (Klinik) Humangenetik
Studium Querschnittsbereiche Epidemiologie / Med. Biometrie
ISBN-10 0-19-989584-8 / 0199895848
ISBN-13 978-0-19-989584-7 / 9780199895847
Zustand Neuware
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