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Hormone Receptors in Breast Cancer -

Hormone Receptors in Breast Cancer

Suzanne A. W. Fuqua (Herausgeber)

Buch | Softcover
281 Seiten
2014 | 2009 ed.
Springer-Verlag New York Inc.
978-1-4899-9680-0 (ISBN)
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Hormone Receptors in Breast Cancer provides an up-to-date resource of the role of hormone receptors in breast cancer written in depth for both the basic molecular academic researcher and translational scientist.
Hormone Receptors in Breast Cancer provides an up-to-date resource of the role of hormone receptors in breast cancer written in depth for both the basic molecular academic researcher and translational scientist. Advances in basic science of molecular endocrinology have undoubtedly been translated into clinical practice, and clinicians caring for this disease need to be knowledgeable about these developments. The molecular basis of hormone action has been elucidated, and the relative significance of the different estrogen and progesterone receptor isoforms has been explored. This explosion of information has lead to exciting new areas of gene specific targeting of the disease, and breast cancer prevention. Paradigm shifts in treatment options and sequencing have recently occurred in breast cancer management, necessitating close cooperation and communication between translational scientists and physicians. This book is focused on providing this communication.

Hormone Action and Clinical Significance of the Estrogen Receptor #x03B1;.- Role of ER#x03B2; in Clinical Breast Cancer.- Hormone Action and Breast Cancer.- Estrogen Receptors in Breast Tumors of African American Patients.- BRCA1 Cross-Talk with Hormone Receptors.- Metastasis of Hormone Receptor Positive Breast Cancer.- Endocrine Therapy with Selective Estrogen Receptor Modulators (SERMs) and Aromatase Inhibitors in the Prevention and Adjuvant Therapy Settings.- Biomarkers in Neoadjuvant Trials.- Hormone Resistance.- Strategies of Hormonal Prevention.- Estrogen Receptor Phenotypes Defined by Gene Expression Profiling.

Erscheint lt. Verlag 20.10.2014
Reihe/Serie Cancer Treatment and Research ; 147
Zusatzinfo X, 281 p.
Verlagsort New York
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Gynäkologie / Geburtshilfe
Medizinische Fachgebiete Innere Medizin Endokrinologie
Medizinische Fachgebiete Innere Medizin Hämatologie
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
ISBN-10 1-4899-9680-X / 148999680X
ISBN-13 978-1-4899-9680-0 / 9781489996800
Zustand Neuware
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