Environmental Radiation Effects on Mammals

A Dynamical Modeling Approach

Olga A. Smirnova (Autor)

Buch | Softcover

214 Seiten

2014
Springer-Verlag New York Inc.
978-1-4899-8238-4 (ISBN)

Artikel merken

Themonographisdevotedtothetheoreticalstudiesofradiationeffectsonmammals. It summarizes the results obtained by the author over the past 30 years, most of them being of high priority. In the course of these studies, a single approach to the modeling of radiation effects on mammals has been elaborated. Speci?cally, in the framework of the developed deterministic mathematical models, the effects of both acute and chronic irradiation in a wide range of doses and dose rates on vital body systems (hematopoiesis, small intestine, and humoral immunity), as well as on the development of autoimmune diseases, are investigated. The radiation effects on the mortality dynamics in homogeneous and nonhomogeneous(in radiosensitivity) mammalian populations are also studied by making use of the developed stochastic models. The most appealing feature of these mortality models consists of the fact that they account for the intrinsic properties of the exposed organism. Namely, within these models the stochastic biometrical functions are calculated proceeding from statistical characteristics and dynamics of the respective critical body system (hematopoiesis or small intestine). The performed theoretical investigations contribute to the development of the system and quantitative approaches in radiation biology and ecology. These studies elucidate the major regulatory mechanisms of the damage and recovery processes running in the vital body systems of exposed mammals and reveal the key par- eters characterizing the processes.

Dr. Olga Andreevna Smirnova is currently a physicist and researcher at the Federal State Unitary Enterprise Research and Technical Center of Radiation-Chemical Safety and Hygiene, Moscow, Russia. She received her Doctor of Physical and Mathematical Sciences degree from Moscow State University, Russia. Dr. Smirnova's fields of study and expertise are modeling the dynamics of various biological systems in mammals exposed to acute/chronic radiation. Dr. Smirnova is associate member of the Scientific Commision F (Life Sciences as Related to Space) of Committee on Space Research (COSPAR). She has authored over 140 articles published in scientific journals and scientific monographs in the fields of mathematical modeling, biophysics, and space science.

Radiation Effects on the Blood-Forming System.- The Small Intestine as a Target for Radiation.- Radiation and Humoral Immunity.- Modeling of Autoimmune Processes.- Individual-Based Approach to Radiation Risk Assessment.

Erscheint lt. Verlag	19.10.2014
Zusatzinfo	XIII, 214 p.
Verlagsort	New York
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Mathematik / Informatik ► Mathematik ► Algebra
	Mathematik / Informatik ► Mathematik ► Angewandte Mathematik
	Medizinische Fachgebiete ► Radiologie / Bildgebende Verfahren ► Radiologie
	Naturwissenschaften ► Biologie ► Zoologie
	Naturwissenschaften ► Physik / Astronomie ► Angewandte Physik
ISBN-10	1-4899-8238-8 / 1489982388
ISBN-13	978-1-4899-8238-4 / 9781489982384
Zustand	Neuware