Frontiers in Colorectal Disease (eBook)

St. Mark's 150th Anniversary International Conference

R. C. G. Russell, J. P. S. Thomson (Autoren)

eBook Download: PDF

2013 | 1. Auflage
160 Seiten
Elsevier Science (Verlag)
978-1-4831-9207-9 (ISBN)

Infos

Frontiers in Colorectal Disease presents a compilation of articles from the international conference titled 'Frontiers in Colorectal Disease'. It discusses the aspects of functional disorders, neoplastic disease and inflammatory bowel disease. It addresses the practical management of a variety of disorders of the colon, rectum, and anus. Some of the topics covered in the book are the basis of functional intestinal symptoms; nervous control of the gut; physiological reactions of the gastrointestinal tract to stress; visceral pain; mechanisms of flatulence and diarrhoea; pathophysiology of constipation; Arbuthnot Lane's disease; and megacolon in adults. The results of surgical treatment of constipation are fully covered. The anorectal incontinence of electrophysiological tests is discussed in detail. The text describes in depth the risk factors in childbirth causing damage to the pelvic floor innervation. A retrospective study of the results of post-anal repair is presented completely. A chapter is devoted to the gracilis muscle transposition for anal incontinence. Another section focuses on the magnitude of risk for cancer in patients with colorectal adenomas. The book can provide useful information to doctors, surgeons, students, and researchers.

Inhalt

Front Cover 1
Frontiers in Colorectal Disease 4
Copyright Page 5
Table of 
6 
Introduction 10
Part I: Symposium I—The basis of functional intestinal symptoms 11
Chapter 1. 
11 
References 12
Chapter 2. Physiological reactions of the gastrointestinal tract to stress 12
References 12
Chapter 3. 
13 
References 14
Chapter 4. Mechanisms of flatulence and diarrhoea 14
Normal defaecation mechanism 15
Defaecation mechanism in patients with the irritable bowel syndrome 15
Mechanism of excessive passage of fluid: true diarrhoea 15
Mechanisms of excessive passage of gas 15
References 15
Part II: 
16 
Chapter 5. Pathophysiology of constipation 16
Mouth to caecum 16
The colon 16
Defaecation 16
Neuropsychiatrie factors 17
Hormones and regulatory peptides 17
References 17
Chapter 6. Arbuthnot Lane's disease: chronic intestinal stasis 17
Definition 18
Research studies 18
Treatment 19
References 19
Chapter 7. 
19 
Patients and methods 19
Results 20
Discussion 21
References 21
Chapter 8. Constipation: results of surgical treatment 21
References 22
Part III: 
23 
Chapter 9. Anorectal incontinence: electrophysiological tests 23
Electromyography (EMG 23
Which test? 24
Motor conduction studies 23
References 24
Chapter 10. Risk factors in childbirth causing damage to the pelvic floor innervation 24
Patients and methods 24
Results 25
Discussion 26
References 26
Chapter 11. Results of postanal repair: a retrospective study 26
Patients 27
Results 27
Discussion 27
References 28
Chapter 12. 
28 
Methods 28
Results 28
Discussion 29
References 30
Chapter 13. Gracilis muscle transposition for anal incontinence: late results 30
Methods 30
Results 30
Discussion 31
References 31
Part IV: 
32 
Chapter 13. Magnitude of risk for cancer in patients with colorectal adenomas 32
Results 32
Discussion 34
References 34
Chapter 14. Polyp follow-up: how, who for and how often? 34
Who's at risk for further polyps (or cancer)? 35
How often need examinations be? 35
References 35
Chapter 15. Follow-up after removal of colorectal adenomas and radical surgery for colorectal carcinomas 35
Patients and methods 35
Results 36
Discussion 37
References 37
Part V: 
38 
Chapter 16. The rectum in adenomatous polyposis: the St. Mark's policy 38
Patients studied 38
Results 38
Discussion 40
References 40
Chapter 17. Familial polyposis 
40 
Surgical management 40
Discussion 41
References 41
Chapter 18. HLA and genetic marker studies in adenomatous polyposis 41
The HLA study 41
DNA polymorphism studies 43
References 44
Part VI: 
45 
Chapter 19. Experimental intestinal carcinogenesis 45
Dietary fat 45
Dietary fibre 45
Minor dietary factors 46
References 46
Chapter 20. Cancer of the large bowel : human carcinogenesis 46
Genetics and environment 46
Epidemiology of large bowel cancer in populations 47
Large bowel cancer in individuals 47
Role of bile acids in large bowel carcinogenesis 47
Re-evaluation of the epidemiological studies of diet 47
References 48
Chapter 21. 
48 
Chromosome aberrations and oncogenes in cancer cells 48
Studies on inherited tumours 48
Applications to colorectal cancer 50
References 50
Part VII: 
51 
Chapter 22. 
51 
Screening 51
Pathology 51
Monitoring disease 51
Treatment 51
References 51
Chapter 23. 
52 
References 53
Chapter 24. Carcinoembryonic antigen and recurrent colorectal cancer 53
The pre-operative serum CEA assay 53
Serial postoperative serum CEA as an early indicator of recurrence 53
MIH/CRC controlled trial of CEA-prompted second look surgery 54
References 54
Part VIII: 
56 
Chapter 26. Clinicopathological staging of colorectal cancer: has the time arrived? 56
Australian Clinicopathological Staging system 56
Definition of terms 56
Discussion 57
References 57
Appendix: Australian Clinicopathological Staging (ACPS) system 57
Chapter 27. 
58 
Ultrasound 58
CT scanning 58
Staging 59
Magnetic resonance 59
Angiography 59
Discussion 59
References 59
Chapter 28. 
60 
Method 60
Results 60
Discussion 61
References 61
Part IX: Symposium IX - Local excision for colorectal cancer 62
Chapter 29. Histological criteria for local excision 62
Methods of examination 62
Reporting 'total biopsies' 62
Discussion 63
References 63
Chapter 30. Indications for local excision of rectal cancer 63
Patients and methods 63
Results 65
Discussion 65
References 65
Chapter 31. Techniques of local surgical excision for rectal carcinoma 66
Methods 66
Discussion 67
References 67
Part X: 
68 
Chapter 32. Adjuvant radiotherapy in rectal cancer: the MRC trials 68
MRC trials 68
Discussion 70
References 71
Chapter 33. Pre-operative radiotherapy in operable rectal cancer: interim report of a trial carried out by the Rectal Cancer Group 71
Protocol 71
Interim results 72
Discussion 73
References 73
Chapter 34. Radiation therapy and rectal carcinoma: The Princess Margaret Hospital experience 73
Radical radiation therapy 73
Adjuvant irradiation 74
Clinical staging 74
References 75
Part XI: 
76 
Chapter 35. Faecal occult blood testing: sensitivity and specificity 76
Faecal occult blood testing as a screen for colorectal cancer 76
How do faecal occult blood tests compare with other screening tests for colorectal cancer 76
Radiochromium: the 'gold standard' of gastrointestinal blood loss 76
Sensitivity and specificity for blood or for tumours 77
Factors influencing the sensitivity and specificity of chemical tests for faecal occult blood 77
Other chemical tests for faecal occult blood 77
New developments 77
Discussion 77
References 78
Chapter 36. A control trial of faecal occult blood screening for colorectal cancer: 2-year results 78
Patients and methods 78
Results 78
Discussion 79
References 80
Chapter 37. The feasibility of large scale population screening 80
Material and methods 80
Results 80
Discussion 81
References 81
Chapter 38. Dark red bleeding as a marker for large bowel neoplasms: a pilot study 81
Method 82
Results 82
Discussion 83
References 83
Part XII: 
84 
Chapter 39. 
84 
Indications for ileorectal anastomosis 84
Technical aspects 84
The St. Mark's series 84
Comparison between IRA and ileo-anal reservoir 84
Discussion 85
References 85
Chapter 40. Restorative proctocolectomy with ileal reservoir 85
Patients and methods 85
Results 86
Discussion 87
References 88
Chapter 41. 
89 
Some aspects of surgical technique 89
Clinical results 90
Discussion 91
References 91
Part XIII: 
92 
Chapter 42. Dysplasia and cancer in inflammatory bowel disease 92
Classification 92
Evaluation of dysplasia 92
Surveillance 92
Discussion 92
References 92
Chapter 43. Cancer risk in ulcerative colitis: surveillance or surgery 93
Problems in measurement of the cancer risk in ulcerative colitis 93
Follow-up study at St Mark's Hospital of patients with extensive colitis 93
Results 93
Comments on the survey 93
Discussion. A suggested policy 94
References 95
Part XIV: 
96 
Chapter 44. 
96 
Epidemiology 96
Diagnosis 96
Treatment 97
Drugs 97
Drugs in localized disease 98
Elemental diets 98
Surgery 98
Discussion 98
References 98
Chapter 45. 
99 
Patients and methods 99
Discussion 99
References 100
Chapter 46. 
101 
Clinical features 101
Management 101
Electrolyte replacement 101
Dietary manipulation 101
Dietary supplements 101
Discussion 102
References 102
Chapter 47. The management of internal fistulae in Crohn's disease 102
Patients and methods 102
Discussion 103
References 103
Chapter 48. 
104 
References 105
Chapter 49. Epidermoid cancer of the anus 106
Anatomy 106
Pathology 106
Clinical features and diagnosis 107
Staging 107
Results of treatment 107
Conclusions 111
References 111
Chapter 50. Continuing experience with single layer appositional anastomosis in the large bowel 113
Patients and methods 113
Results 113
Discussion 114
Acknowledgements 114
References 114
chapter 51. Effect of adjuvant chemo- or immunotherapy on the prognosis of colorectal cancer operated for cure 116
Material and methods 116
Results 117
Discussion 118
References 119
chapter 52. Evacuation proctography in obstructed defaecation and rectal intussuception 120
Patients and methods 120
Results 121
Discussion 124
References 124
chapter 53. Intrarectal ultrasound and computed tomography in pre- and postoperative assessment of patients with rectal cancer 126
Methods 126
Results 126
Discussion 127
References 127
Abstracts for free papers 129
Abstracts for posters 144
Index 154
Published monthly for the British Journal of Surgery Society Ltd by Butterworth Scientific Ltd 159
An important new title from Butterworths 160
If you were allowed just one work on surgical practice this would have to be it.Rob & Smith's Operative Surgery 4th Edition

Produkt-Details

• Erscheint lt. Verlag: 22.10.2013
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Chirurgie
• Themenwelt: Naturwissenschaften ► Biologie
• Themenwelt: Technik
• ISBN-10: 1-4831-9207-5 / 1483192075
• ISBN-13: 978-1-4831-9207-9 / 9781483192079