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Heart Rate and Rhythm -

Heart Rate and Rhythm

Molecular Basis, Pharmacological Modulation and Clinical Implications
Buch | Softcover
XXII, 678 Seiten
2014 | 2011
Springer Berlin (Verlag)
978-3-642-44579-8 (ISBN)
CHF 299,55 inkl. MwSt
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Heart Rate and Rhythm provides an important context for understanding the complicated molecular and cellular mechanisms that underlie normal and pathophysiological cardiac rhythms.

Pathological heart rhythms are a major health issue. In this book experts from various fields provide an important context for understanding the complicated molecular and cellular mechanisms that underlie normal and pathophysiological cardiac rhythms.

Individual chapters cover a full range of topics, including the ionic basis of pacemaking, the role of specific channels and transporters in sinoatrial node pacemaking, altered intracellular Ca2+ handling in response to disease, computer modeling of the action potentials of pacemaker and working cardiomyocytes, genetic and molecular basis of inherited arrhythmias and a review of established and novel antiarrhythmic agents. Due to the key importance of the specialized pacemaker cells and tissue (sinoatrial and atrioventricular nodes) in maintaining heart rate and rhythm, special emphasis is placed on the peculiar electrophysiology of these cells.

Normal Cardiac Rhythm and Pacemaker Activity.- Modeling of Rhythm in the Heart.- Cardiac Development and Anatomy.- Mechanisms of Acquired Arrhythmia.- Mechanisms of Inherited Arrhythmia.- Role of Specific Channels and Transporters in Arrhythmia.- Drugs and Cardiac Arrhythmia.

From the reviews:

"Heart Rate reigns as one of 2011's best. Here, physicians are presented with an acute review of how changes in heart rate can be used as a marker to assess patients in the clinical setting. ... the writers also extend their treatise to practicing clinicians and ways that the information can be used to better treat patients. Noted for its clear delineation of complex data; with skilled use of illustrations and graphs that re-enforce key points chapter-by-chapter." (John Aiello, The Electric Review, July, 2011)

Erscheint lt. Verlag 11.10.2014
Zusatzinfo XXII, 678 p.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 1056 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Studium 1. Studienabschnitt (Vorklinik) Physiologie
Naturwissenschaften Biologie Genetik / Molekularbiologie
Schlagworte Action potentials • Arrhythmogenesis • Atrioventricular junction • Cardiac pacemaker • Intracellular Ca • ion channels • Myocard • Purkinje fibres
ISBN-10 3-642-44579-9 / 3642445799
ISBN-13 978-3-642-44579-8 / 9783642445798
Zustand Neuware
Informationen gemäß Produktsicherheitsverordnung (GPSR)
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