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Handbook on the Toxicology of Metals -

Handbook on the Toxicology of Metals (eBook)

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2014 | 4. Auflage
1542 Seiten
Elsevier Science (Verlag)
978-0-12-397339-9 (ISBN)
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Handbook on the Toxicology of Metals, Fourth Edition bridges the gap between established knowledgebase and new advances in metal toxicology to provide one essential reference for all those involved in the field. This book provides comprehensive coverage of basic toxicological data, emphasizing toxic effects primarily in humans, but also those of animals and biological systems in vitro. The fourth edition also contains several new chapters on important topics such as nanotoxicology, metals in prosthetics and dental implants, gene-environment interaction, neurotoxicology, metals in food, renal, cardiovascular, and diabetes effects of metal exposures and more.

Volume I covers 'General Considerations” and Volume II is devoted to 'Specific Metals.” A multidisciplinary resource with contributions from internationally-recognized experts, the fourth edition of the Handbook on the Toxicology of Metals is a prominent and indispensable reference for toxicologists, physicians, pharmacologists, engineers, and all those involved in the toxicity of metals.


  • Contains 61 peer reviewed chapters dealing with the effects of metallic elements and their compounds on biological systems
  • Includes information on sources, transport and transformation of metals in the environment and on certain aspects of the ecological effects of metals to provide a basis for better understanding of the potential for adverse effects on human health
  • Covers the toxicology of metallic nanomaterials in a new comprehensive chapter
  • Metal toxicology in developing countries is dealt with in another new chapter emphasizing the adverse effects on human health by the inadequate handling of 'ewaste”
  • Other new chapters in the 4th edition include:  Toxic metals in food; Toxicity of metals released from medical devices; Gene-environment interactions; Neurotoxicology of metals; Cardiovascular disease; Renal effects of exposure to metals; Gold and gold mining; Iridium; Lanthanum; Lithium and Rhodium

Handbook on the Toxicology of Metals, Fourth Edition bridges the gap between established knowledgebase and new advances in metal toxicology to provide one essential reference for all those involved in the field. This book provides comprehensive coverage of basic toxicological data, emphasizing toxic effects primarily in humans, but also those of animals and biological systems in vitro. The fourth edition also contains several new chapters on important topics such as nanotoxicology, metals in prosthetics and dental implants, gene-environment interaction, neurotoxicology, metals in food, renal, cardiovascular, and diabetes effects of metal exposures and more. Volume I covers "e;General Considerations? and Volume II is devoted to "e;Specific Metals.? A multidisciplinary resource with contributions from internationally-recognized experts, the fourth edition of the Handbook on the Toxicology of Metals is a prominent and indispensable reference for toxicologists, physicians, pharmacologists, engineers, and all those involved in the toxicity of metals. Contains 61 peer reviewed chapters dealing with the effects of metallic elements and their compounds on biological systems Includes information on sources, transport and transformation of metals in the environment and on certain aspects of the ecological effects of metals to provide a basis for better understanding of the potential for adverse effects on human health Covers the toxicology of metallic nanomaterials in a new comprehensive chapter Metal toxicology in developing countries is dealt with in another new chapter emphasizing the adverse effects on human health by the inadequate handling of "e;ewaste? Other new chapters in the 4th edition include: Toxic metals in food; Toxicity of metals released from medical devices; Gene-environment interactions; Neurotoxicology of metals; Cardiovascular disease; Renal effects of exposure to metals; Gold and gold mining; Iridium; Lanthanum; Lithium and Rhodium

List of Contributors


Jan Aaseth, M.D., Ph.D.,     Professor Department of Medicine, Innlandet Hospital Trust and Hedmark University College, Kongsvinger, Norway

Peter Aggett, M.Sc., FRCPCH,     Honorary Professor, Medical School, Lancaster University, Lancaster, UK

Antero Aitio, M.D., Ph.D.,     Professor Emeritus, Finnish Institute of Occupational Health, Helsinki, Finland

Jan Alexander, M.D., Ph.D.,     Professor, Deputy Director-General, Norwegian Institute of Public Health, Oslo, Norway

Shegufta Ameer, M.Sc.,     Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden

Christian B.I. Andersen, Cand. Scient.,     Biologist, Department of Environmental Affairs, Team Nature, Municipality of Kerteminde, Kerteminde, Denmark

Ole Andersen, Dr. Med,     Professor, Department of Science, Systems, and Models, Roskilde University, Roskilde, Denmark

Pietro Apostoli, M.D.,     Professor, Unit of Occupational Health and Industrial Hygiene, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy

Michael Aschner, Ph.D.,     Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA

Farida Louise Assem, Ph.D.,     Senior Toxicologist, ToxMinds B.V.B.A., Brussels, Belgium

Lars Barregård, M.D., Ph.D.,     Chief Physician and Professor, Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital and Academy, Gothenburg, Sweden

David C. Bellinger, Ph.D.,     Professor of Neurology at Harvard Medical School, and Professor in the Department of Environmental Health at the Harvard School of Public Health, Boston Children’s Hospital, Boston, MA, USA

Ingvar A. Bergdahl, Ph.D.,     Associate Professor, Occupational Medicine, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden

Maths Berlin, M.D., Ph.D.,     Professor Emeritus of Environmental Medicine, Lund University, Lund, Sweden

Balázs Berlinger, Ph.D.,     Senior Engineer, National Institute of Occupational Health, Oslo, Norway

Alfred Bernard, Ph.D.,     Professor, Louvain Centre for Toxicology and Applied Pharmacology, Brussels, Belgium

Carolina Bigert, M.D., Ph.D.,     Chief Physician, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

Poul Bjerregaard, Ph.D.,     Professor of Ecotoxicology, Institute of Biology, University of Southern Denmark, Odense, Denmark

Robyn Blain, M.S., Ph.D.,     Technical Specialist, ICF International, Fairfax, VA, USA

Karin Broberg, Ph.D.,     Associate Professor, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

Jason Brocato,     Department of Environmental Medicine, NYU School of Medicine, New York, NY, USA

Ronald P. Brown,     Toxicologist, Laboratory of Toxicology and Biocompatibility, CDRH Office of Science and Engineering Laboratories, US FDA, Silver Spring, MD, USA

Esben Budtz-Jørgensen, M.Sc., Ph.D.,     Section of Biostatistics, University of Copenhagen, Copenhagen, Denmark

Samuel W. Caito, Ph.D.,     Department of Pediatrics, Medical Center North, Vanderbilt University Medical Center, Nashville, TN, USA

Simona Catalani, Ph.D.,     Unit of Occupational Health and Industrial Hygiene, Department of Medical and Surgical Specialities, Radiological Science and Public Health, University of Brescia, Brescia, Italy

C.-J. Chen, Sc.D.,     M.P.H.Genomics Research Center, Taipei, Taiwan

C.-H. SeleneJ. Chou, Ph.D.,     Division of Toxicology and Human Health Sciences Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA

Max Costa, Ph.D.,     Professor and Chairman, Department of Environmental Medicine, NYU School of Medicine, New York, NY, USA

Todd Davidson, Ph.D., DABT,     Manager—EHS, Environmental/Occupational Toxicologist, New Brunswick, NJ, USA

John W. Eaton, Ph.D., MDHc,     Professor, Deputy Director, James Graham Brown Cancer, University of Louisville, Louisville, KY, USA

Alison Elder, Ph.D.,     Associate Professor, Department of Environmental Medicine, University of Rochester, Rochester, NY, USA

Carl -Gustaf Elinder, M.D., Ph.D.,     Professor, Head of Department of Evidence-Based Medicine, Stockholm County Council, Stockholm, and Professor of Renal Medicine, Karolinska Institutet, Stockholm, Sweden

Dag G. Ellingsen, M.D., Ph.D.,     Head of Department, Department of Chemical and Biological Work Environment, National Institute of Occupational Health, Oslo, Norway

Hisham A. El-Masri,     Agency for Toxic Substances and Disease Registry, Computational Toxicology Laboratory, Division of Toxicology, Atlanta, GA, USA

Karin Engström, Ph.D.,     Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden

Bengt Fadeel, M.D., Ph.D.,     Professor, Nanosafety & Nanomedicine Laboratory, Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

Obaid M. Faroon, D.V.M., Ph.D.,     Agency for Toxic Substances and Disease Registry, Division of Toxicology and Environmental Medicine, Atlanta, GA, USA

Bruce A. Fowler, Ph.D., A.T.S.,     Adjunct Professor, Rollins School of Public Health, Emory University, Atlanta, GA, and Presidents Rotating Professor, Center for Alaska Native Health Research, University of Alaska Fairbanks, Fairbanks, AK, USA

Silvia Fustinoni, Ph.D.,     Professor, Laboratory of Toxicology, Department of Clinical Sciences and Community Health, University of Milano and Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy

Lars Gerhardsson, M.D., Ph.D.,     Professor and Chief Physician, Occupational and Environmental Medicine, Sahlgrenska Academy and University Hospital, Gothenburg, Sweden

Philippe Grandjean, M.D., D.M.Sc.,     Professor, Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, DK-5000 Odense, Denmark

Per Gustavsson, M.D., Ph.D.,     Professor, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

James S. Holler, Ph.D.,     Program Leader, Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA

Per Hultman, M.D., Ph.D.,     Professor, Division of Molecular and Immunological Pathology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, and Pathology Clinic, Östergötland County Council, Linköping, Sweden

Ivo Iavicoli, M.D., Ph.D.,     Division of Occupational Medicine, Institute of Public Health Catholic University of Sacred Heart, Roma, Italy

Anders Iregren, Ph.D.,     Associate Professor, Toxicological Risk Assessment, Swedish Work Environment Authority, Stockholm, Sweden

Marek Jakubowski, Ph.D.,     Professor, Department of Chemical Hazards, Nofer Institute of Occupational Medicine, Lodz, Poland

Taiyi Jin, M.D., Ph.D.,     Professor, Department of Occupational Health, School of Public Health, Fudan University (Shanghai Medical University), Shanghai, PR China

Robert L. Jones,     National Center for Environmental Health, Centers for Disease Control...

Erscheint lt. Verlag 7.8.2014
Sprache englisch
Themenwelt Studium 2. Studienabschnitt (Klinik) Pharmakologie / Toxikologie
Studium Querschnittsbereiche Epidemiologie / Med. Biometrie
ISBN-10 0-12-397339-2 / 0123973392
ISBN-13 978-0-12-397339-9 / 9780123973399
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