Hepatic Steatosis

Clinical Risk Factors, Molecular Mechanisms and Treatment Outcomes

Buch | Hardcover

306 Seiten

2014
Nova Science Publishers Inc (Verlag)
978-1-63321-403-3 (ISBN)

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In the last few years, human metabolic disorders have become some of the most prevalent and prejudicial diseases worldwide. Hepatic steatosis, among many health problems, has several risk factors related to the disease prognosis such as obesity, nutritional problems, diabetes, hypertension, hyperuricemia, and even sleep apnea. Alcohol abuse also can lead to a severe liver-steatosis state. The progression of hepatic steatosis can lead to complications such as cryptogenic cirrhosis and hepatocellular carcinoma. Drug therapy has instead been focused on the mitigation of risk factors, however new potential therapeutic perspectives are being discussed. This book presents the origins, diagnosis and epidemiology of hepatic steatosis with new perceptions. The authors also aimed to show the molecular basis and signaling involved in liver disorders, discussing the inflammatory process, lipid metabolism and angiogenesis mechanisms. The role of nutrition in the treatment and development of steatosis was also presented and new advances were highlighted. Recent studies revealed the need for the use of bariatric surgery, functional foods and the modulation of endogenous systems, such as the sirtuins and renin-angiotensin systems, to treat liver disease. In this context, we aimed to introduce, review and discusses one of the most widespread metabolic disorders in the world: hepatic steatosis and its repercussions.

PrefaceUnit 1: GENESIS, DIAGNOSIS AND TREATMENTSChapter 1: Hepatic Steatosis: Origins, Epidemiology and Pharmacological Treatments(Simone M. Macedo, Jamille F Lula, Lucineia de Pinho and Sergio H S Santos, Laboratory of Health Science, Postgraduate Program in Health Science, Universidade Estadual de Montes Claros (Unimontes), Montes Claros, MG, and Institute of Biological Sciences (ICB). Pharmacology Department, Universidade Federal de Minas Gerais (UFMG) Belo Horizonte, MG, Brasil)Chapter 2: Non Alcoholic Fatty Liver Disease: Clinical, Laboratory and Imaging Diagnostic Methods(Antonio S.B. Jorge, Gislaine C.B. Jorge and Thaisa S. Crespo, Universidade Estadual de Montes Claros, Montes Claros, MG, Brazil) For Complete Table of Contents, please visit our website athttps://www.novapublishers.com/catalog/product_info.php?products_id=50501

Verlagsort	New York
Sprache	englisch
Maße	178 x 254 mm
Gewicht	678 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Hepatologie
ISBN-10	1-63321-403-6 / 1633214036
ISBN-13	978-1-63321-403-3 / 9781633214033
Zustand	Neuware