Myeloproliferative Disorders

Symptoms, Risk Factors and Treatment Options

Buch | Softcover

112 Seiten

2014
Nova Science Publishers Inc (Verlag)
978-1-63321-201-5 (ISBN)

Artikel merken

Myeloproliferative disorders are a group of clonal haematological neoplasms characterised by proliferation of one or more cells of myeloid lineage. They are the result of acquired mutations in the progenitor cell leading to hyper proliferation or neoplastic expansion of more mature forms of myeloid cells. Cells retain their functional ability with some degree of defects and also lead to suppression of normal stem cells. The most common type of Myeloproliferative Neoplasms (MPN) can broadly be classified into BCR ABL positive (Chronic Myelogenous Leukemia) and BCR ABL negative Disorders (Polycythemia Vera PV, Essential Thrombocytosis ET and Primary Myelofibrosis PMF). There are other rare types which have relatively low incidence like chronic neutrophilic leukemia, chronic eosinophilic leukemia, systemic mastocytosis and myeloproliferative neoplasms unclassifiable. These are the indolent type of haematological malignancies associated with marrow hypercellularity and organomegaly, with gradual progression to myelofibrosis or transformation to acute leukemias. During the dormant course of the BCR ABL negative MPN, they are more prone to thrombo-hemorrhagic complications and the treatment strategy is directed mostly to prevent complications. The past decade; therapies for BCR ABL positive disease (CML) have been a milestone achievement in keeping the disease in remission for many years, preventing major complications and halting the progression of the disease. This book discusses the classification, diagnosis and treatment of myeloproliferative diseases and provides insight on the symptoms and risk factors involved in the diseases.

PrefaceMyeloproliferative Diseases: Classification, Diagnosis and Treatment(Farhan Mohammad, FNU Vikram, Wajeeha Saeed, George Everett, Amr Lal, Muhammad Rizwan Sardar, Staten Island University Hospital, Staten Island, NY, USA, and others)Histopathology and Diagnostic Approaches to the Myeloproliferative Neoplasms(Christina Salazar, Sanjeev M. Balamohan, Patrick D. Millikan, Wendy H. Raskind, Melissa A. Kacena, Indiana University School of Medicine, Indianapolis, IN, USA, and others)For Complete Table of Contents, please visit our website athttps://www.novapublishers.com/catalog/product_info.php?products_id=50211

Erscheint lt. Verlag	1.9.2014
Verlagsort	New York
Sprache	englisch
Maße	152 x 229 mm
Gewicht	236 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Hämatologie
ISBN-10	1-63321-201-7 / 1633212017
ISBN-13	978-1-63321-201-5 / 9781633212015
Zustand	Neuware