Bone and Joint Infections
John Wiley & Sons Inc (Verlag)
978-1-118-58177-3 (ISBN)
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Infections of the bones (osteomyelitis) and joints (septic arthritis) are serious health problems which require antibiotics and often surgery. Awareness among health professionals of the causes and treatment options for various types of bone and joint infections is essential for effective resolution.
Bone and Joint Infections takes a multidisciplinary approach in covering the diagnostic and therapeutic treatment of osteomyelitis and septic arthritis, including different types of implant-associated infections. Correct and rapid diagnosis of bone and joint infection is crucial, and requires the input of a variety of specialists. Bone and Joint Infection takes a similarly collaborative and comprehensive approach, including chapters authored by clinicians, laboratory specialists, and surgeons.
Covering the basic microbiology and clinical aspects of bone and joint infection, this book will be a valuable resource both for researchers in the lab and for physicians and surgeons seeking a comprehensive reference on osteomyelitis and septic arthritis.
Werner Zimmerli, MD, is Professor in Internal Medicine and Infectious Diseases at Basel University Medical Clinic, Liestal, Switzerland.
Contributors xiii
Foreword xvii
Acknowledgments xix
Chapter 1 Introduction 1
Werner Zimmerli
Chapter 2 Microbiology of Bone and Joint Infections 5
Seong Yeol Ryu and Robin Patel
Microorganisms in Osteomyelitis 5
Microorganisms in Implant-Associated Bone and Joint Infection 7
Microorganisms in Native Joint Arthritis 10
Diagnostic Approach in Osteomyelitis 11
Diagnostic Approach in Foreign Body–Associated Infection 12
Diagnostic Approach in Native Joint Infection 15
Novel Diagnostic Procedures 17
Acknowledgment 17
References 17
Chapter 3 Pharmacokinetics and Pharmacodynamics of Antibiotics in Bone 21
Cornelia B. Landersdorfer, Jürgen B. Bulitta, and Fritz Sörgel
Pharmacokinetics 21
Bone Sample Preparation and Analysis 22
Pharmacokinetic Sampling and Data Analysis 23
Penetration of Antibiotics into Bone 24
Pharmacodynamics and Monte Carlo Simulations 31
Conclusions 34
Key Points 34
References 35
Chapter 4 Preclinical Models of Infection in Bone and Joint Surgery 39
Lorenzo Calabro, R. Geoff Richards, and T. Fintan Moriarty
Introduction 39
Influence of Species in Preclinical Models of Bone and Joint Infection 40
Overview of Animal Models 42
Direct Inoculation with Minimal Trauma 42
Animal Osteomyelitis Models Incorporating Trauma 46
Hematogenous Models 47
Future Directions 48
Conclusion 49
Key Points 49
References 49
Chapter 5 Native Joint Arthritis in Children 55
Pablo Yagupsky
Introduction 55
Epidemiology 55
Microbiology 56
Pathogenesis 61
Clinical Presentation 62
Laboratory Investigation 63
Imaging Studies 66
Differential Diagnosis 66
Treatment 67
Prognosis 71
Key Points 72
References 72
Chapter 6 Native Joint Arthritis 77
Ilker Uçkay, Mohamed Al-Mayahi, Domizio Suvà, Daniel Lew, and Pierre Vaudaux
Introduction 77
Pathogenesis, Epidemiology, and Microbiology 77
Diagnosis 79
Treatment 81
Outcome of Native Joint Septic Arthritis 87
Key Points 88
Acknowledgments 88
References 88
Chapter 7 Septic Arthritis of Axial Joints 93
Werner Zimmerli
Septic Arthritis of the Sternoclavicular Joint 93
Key Points 98
Septic Arthritis of the Symphysis Pubis 98
Key Points 103
Septic Arthritis of the Sacroiliac Joint 103
Key Points 107
References 107
Chapter 8 Periprosthetic Joint Infection: General Aspects 113
Werner Zimmerli
Introduction 113
Definition 114
Classification 115
Pathogenesis 115
Diagnostic Algorithm 118
Laboratory Investigation 119
Therapeutic Management 121
Prophylaxis 122
Errors in the Management of PJI 123
Key Points 124
References 124
Chapter 9 Periprosthetic Joint Infection after Total Hip and Knee Arthroplasty 131
Werner Zimmerli and Martin Clauss
Introduction 131
Risk Factors 131
Microbiology 132
Clinical Features 133
Laboratory Investigation 133
Imaging Procedures 134
Management 135
Instructive Cases 142
References 146
Chapter 10 Periprosthetic Joint Infection after Shoulder Arthroplasty 151
Parham Sendi, Beat K. Moor, and Matthias A. Zumstein
Introduction 151
Risk Factors 151
Microbiology 153
Pathogenesis 154
Clinical Features 154
Laboratory Investigation 155
Imaging Procedures 157
Management 158
Instructive Cases 162
References 163
Chapter 11 Periprosthetic Joint Infection after Elbow Arthroplasty 167
Yvonne Achermann and Michael C. Glanzmann
Introduction 167
Microbiology 168
Clinical Features 168
Diagnostic Procedures 169
Instructive Cases 176
References 179
Chapter 12 Periprosthetic Joint Infection after Ankle Arthroplasty 183
Parham Sendi, Bernhard Kessler, and Markus Knupp
Introduction 183
History of Total Ankle Arthroplasty 184
Risk Factors 185
Microbiology 186
Management 189
Instructive Cases 192
References 194
Chapter 13 Osteomyelitis: Classification 197
Werner Zimmerli
Classification According to Pathogenesis 197
Classification According to the Duration of Infection 199
Classification According to the Localization 200
Classification According to the Presence of an Implant 200
Classification According to Anatomy and Comorbidity 200
References 201
Chapter 14 Osteomyelitis in Children 205
Priya Sukhtankar, Saul N. Faust, and Nicholas M.P. Clarke
Introduction 205
Epidemiology 205
Pathophysiology 206
Clinical Presentation, Diagnosis, and Microbiology 207
Treatment 214
Complications 217
Key Points 217
References 217
Chapter 15 Acute Osteomyelitis in Adults 221
Werner Zimmerli
Introduction 221
Pathogenesis 221
Epidemiology 223
Microbiology 224
Risk Factors 225
Clinical Features 227
Laboratory Investigation 229
Imaging Procedures 231
Clinical and Imaging Differential Diagnosis 232
Treatment 233
Key Points 236
References 236
Chapter 16 Subacute Osteomyelitis: Tuberculous and Brucellar Vertebral Osteomyelitis 241
Juan D. Colmenero and Pilar Morata
Introduction 241
Epidemiology 241
Clinical Features 242
Laboratory Investigation 244
Imaging Procedures 247
Antimicrobial and Surgical Therapy 250
Key Points 252
References 252
Chapter 17 Chronic Osteomyelitis in Adults 257
Silvin Lito, Antoine Lomessy, Pierre Vaudaux, and Ilker Uçkay
Introduction 257
Epidemiology and Pathogenesis 259
Diagnosis 260
Treatment 262
Future Perspectives 268
Key Points 268
Acknowledgments 269
References 269
Chapter 18 Diabetic Foot Osteomyelitis 273
Eric Senneville and Sophie Nguyen
Introduction 273
Classification 273
Microbiology 276
Risk Factors 278
Clinical Features 279
Inflammatory Parameters 279
Imaging Procedures 280
Management 281
Prevention 284
References 284
Chapter 19 Osteomyelitis of the Jaws 289
Werner Zimmerli
Introduction 289
Classification 289
Microbiology 291
Risk Factors 292
Clinical Features 292
Laboratory Investigation 294
Imaging Procedures 296
Management 297
Key Points 299
References 299
Chapter 20 Implant-Associated Osteomyelitis of Long Bones 303
Martin McNally and Parham Sendi
Introduction 303
Classification and Risk Factors 304
Microbiology 306
Clinical Features 306
Laboratory Investigation 307
Imaging Procedures 309
Management 309
Instructive Cases 317
References 320
Chapter 21 Implant-Associated Vertebral Osteomyelitis 325
Todd J. Kowalski
Introduction 325
Epidemiology, Risk Factors, and Preventive Measures 326
Microbiology 327
Clinical Features 331
Diagnostic Procedures 332
Management 333
Instructive Cases 339
References 341
Chapter 22 Postoperative Sternal Osteomyelitis 347
Parham Sendi, Örjan Friberg, Mihai A. Constantinescu, and Lars Englberger
Introduction 347
Risk Factors 348
Microbiology 351
Clinical Features 352
Laboratory Investigation 354
Imaging Procedures 355
Management 356
Instructive Cases 360
References 362
Index 367
| Verlagsort | New York |
|---|---|
| Sprache | englisch |
| Maße | 181 x 250 mm |
| Gewicht | 860 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Orthopädie |
| Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
| Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
| Naturwissenschaften ► Biologie ► Ökologie / Naturschutz | |
| ISBN-10 | 1-118-58177-6 / 1118581776 |
| ISBN-13 | 978-1-118-58177-3 / 9781118581773 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
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