Nathan and Oski's Hematology and Oncology of Infancy and Childhood

Stuart H. Orkin, David G. Nathan, David Ginsburg, A. Thomas Look (Autoren)

Buch | Hardcover

2591 Seiten | Ausstattung: ExpertConsult

2015 | 8th Revised edition
Saunders (W.B.) Co Ltd (Verlag)
978-1-4557-5414-4 (ISBN)

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Written by the leading names in pediatric oncology and hematology, Nathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color, two-volume set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children.

Section 1 Neonatal Hematology
1. Anatomy and Physiology of Hematopoiesis
2. The Neonatal Erythrocyte and Its Disorders
3. Neonatal Immune Hemolytic Disease
4. Disorders of Bilirubin Metabolism
5. Hemostasis in the Newborn and Infant

Section 2 Bone Marrow Failure
6. Acquired Aplastic Anemia and Pure Red Cell Aplasia
7. Inherited Bone Marrow Failure Syndromes
8. Principles of Bone Marrow and Stem Cell Transplantation

Section 3 Disorders of Erythrocyte Production
9. A Diagnostic Approach to the Anemic Patient
10. Megaloblastic Anemia
11. Disorders of Iron, Lead and Copper Metabolism and Sideroblastic Anemias
12. The Porphyrias

Section 4 Hemolytic Anemias
13. Autoimmune Hemolytic Anemia
14. Paroxysmal Nocturnal Hemoglobinuria and Other Nonimmune Acquired Anemias
15. The Red Cell Membrane
16. Disorders of the Red Cell Membrane
17. Pyruvate Kinase Deficiency and Disorders of Glycolysis
18. Glucose-6-Phosphate Dehydrogenase Deficiency
19. Hemoglobins: Normal and Abnormal

Section 5 Disorders of Hemoglobin
20. Sickle Cell Disease
21. The Thalassemias

Section 6 The Phagocyte System
22. The Phagocyte System and Disorders of Granulopoiesis and Granulocyte Function

Section 7 The Immune System
23. The Immune Response
24. Primary Immunodeficiency Diseases

Section 8 Storage Diseases
25. Storage Diseases of the Reticuloendothelial System

Section 9 Hemostasis
26. Platelets and the Vessel Wall
27. Blood Coagulation
28. The Molecular Basis of Fibrinolysis
29. Clinical and Laboratory Approach to the Patient with Bleeding
30. Inherited Platelet Disorders
31. Hemophilia and von Willebrand Disease
32. Rare Hereditary Coagulation Factor Abnormalities
33. Inherited Disorders of Thrombosis and Fibrinolysis
34. Acquired Platelet Defects
35. Acquired Disorders of Hemostasis

Section 10 Supportive Therapy
36. Transfusion Medicine

Section 11 Hematologic Manifestations of Systemic Diseases
37. Hematological Manifestations of Systemic Diseases
38. Hematology in the Developing World

Section 12 Biology of Cancer
39. Origins and Evolution of Pediatric Cancer
40. Epidemiology of Leukemia in Childhood
41. Childhood Genetic Predisposition Syndromes
42. Epigenetics and Genetics of Childhood Cancers
43. Targeted Therapies in Oncology
44. Cytogenetic and Molecular Pathology of Pediatric Cancer

Section 13 Pediatric Cancer Therapeutics
45. Chemotherapy in the Pediatric Cancer Patient
46. Immunotherapy of Cancer
47. Pediatric Radiation Oncology
48. Pediatric Surgical Oncology

Section 14 Hematologic Malignancy
49. Acute Lymphoblastic Leukemia
50. Pediatric Myeloid Leukemia, Myelodysplasia, and Myeloproliferative Disease
51. Infant Leukemias
52. Malignant Lymphomas and Lymphadenopathies

Section 15 Solid Tumors
53. Neuroblastoma
54. Pediatric Renal Tumors
55. Retinoblastoma
56. Tumors of the Brain and Spinal Cord
57. Hepatoblastomas and Other Liver Tumors
58. Rhabdomyosarcoma
59. Nonrhabodmyosarcomas and Other Soft Tissue Tumors
60. Ewing's Sarcoma
61. Osteosarcoma
62. Pediatric Germ Cell Tumors
63. Histocytoses
64. Rare Tumors of Childhood
65. Diagnostic Imaging in the Evaluation of Childhood Cancer

Section 16 Supportive Care
66. Infectious Disease in the Pediatric Cancer Patient
67. Oncologic Emergencies
68. Nursing Care of Patients with Childhood Cancer
69. Palliative Care in Pediatric Oncology
70. Symptom Management in Children with Cancer
71. Childhood Cancer Survivorship
72. Psychosocial Care of Children and Families
73. Ethical Considerations in Pediatric Oncology Clinical Trials

Appendices
Reference Values in Infancy and Childhood

Erscheint lt. Verlag	24.9.2021
Zusatzinfo	Approx. 1100 illustrations (900 in full color)
Verlagsort	London
Sprache	englisch
Maße	222 x 281 mm
Gewicht	2760 g
Einbandart	gebunden
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Hämatologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pädiatrie
ISBN-10	1-4557-5414-5 / 1455754145
ISBN-13	978-1-4557-5414-4 / 9781455754144
Zustand	Neuware