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Biophysical Effects of Cold Atmospheric Plasma on Glial Tumor Cells

(Autor)

Buch | Hardcover
XIV, 74 Seiten
2014 | 2014
Springer International Publishing (Verlag)
978-3-319-06223-5 (ISBN)

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Biophysical Effects of Cold Atmospheric Plasma on Glial Tumor Cells - Julia Köritzer
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Cold atmospheric plasma is an auspicious new candidate in cancer treatment. Cold atmospheric plasma (CAP) is a partially ionized gas in which the ion temperature is close to room temperature. It contains electrons, charged particles, radicals, various excited molecules and UV photons. These various compositional elements have the potential to inhibit cancer cell activity whilst doing no harm to healthy cells. Glioblastoma (GBM) is the most common and lethal primary brain tumor in adults; treatment including surgery, radio- and chemotherapy remains palliative for most patients as a cure remains elusive. The successful combination of the standard chemotherapeutic temozolomide (TMZ) and CAP treatment features synergistic effects even in resistant glioma cells. In particular in glioma therapy, CAP could offer an innovative approach allowing specific cancer cell / tumor tissue inhibition without damaging healthy cells. Thus CAP is a promising candidate for combination therapy especially for patients suffering from GBMs showing TMZ resistance.

Summary.- Introduction.- Materials and Methods.- Results.- Discussion.- Assessment and Outlook.- Supplementary Data.- References.

Erscheint lt. Verlag 8.8.2014
Reihe/Serie Springer Theses
Zusatzinfo XIV, 74 p. 38 illus., 12 illus. in color.
Verlagsort Cham
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Radiologie
Naturwissenschaften Physik / Astronomie Angewandte Physik
Schlagworte brain tumor • Chemotherapeutic Temozolomide • Cold Atmospheric Plasma • Glioblastoma multiforme • Glioblastoma Treatment • O6-methylguanine-DNA Methyltransferase • O6-methylguanine–DNA Methyltransferase • Plasma in Cancer Treatment • Plasma medicine • Reactive oxygen species
ISBN-10 3-319-06223-9 / 3319062239
ISBN-13 978-3-319-06223-5 / 9783319062235
Zustand Neuware
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