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Mammalian Transient Receptor Potential (TRP) Cation Channels

Volume I

Bernd Nilius, Veit Flockerzi (Herausgeber)

Buch | Hardcover
XII, 726 Seiten
2014 | 2014
Springer Berlin (Verlag)
978-3-642-54214-5 (ISBN)

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This book offers up-to-date information on the molecular and functional properties and pharmacology of mammalian Transient Receptor Potential channels, from close-up views of single protein/channels to broader principles of function and important pathologies.
In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field will describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.

TRPs -Truly Remarkable Proteins.- The TRCP Subfamily: TRPC1.- TRPC2.- TRPC3- a Multifunctional Signaling Molecule.- TRPC4 and TRPC4-Containing Channels.- TRPC5.- TRPC6: Physiological Function and Pathophysiological Relevance.- Transient Receptor Potential Canonical 7 (TRPC7).- The TRPV Subfamily: TRPV1.- TRPV2.- TRPV3.- The TRPV4 Channel.- TRPV5, a Ca2+ Channel for the Fine Tuning of Ca2+ Reabsorption.- TRPV6 Channels.- The TRPM Subfamily: TRPM1.- TRPM2.- TRPM3.-TRPM4.- TRPM5.- TRPM6.- TRPM7.- TRPM8.- The TRPA1, TRPML and TRPP Subfamily: TRPA1.- TRPML1: An Ion Channel in the Lysosome.- TRPML2 and Mucolipin Evolution.- TRPML3.- TRPP Subfamily and Polycystin-1 Proteins.

Erscheint lt. Verlag 8.5.2014
Reihe/Serie Handbook of Experimental Pharmacology
Zusatzinfo XII, 726 p. 56 illus., 17 illus. in color.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 1266 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Pharmazie
Studium 1. Studienabschnitt (Vorklinik) Physiologie
Schlagworte pain perception • temperature sensors • TRP Channels • TRP pharmacology
ISBN-10 3-642-54214-X / 364254214X
ISBN-13 978-3-642-54214-5 / 9783642542145
Zustand Neuware
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