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Chronic Lymphoid Leukemias

(Autor)

Buch | Hardcover
664 Seiten
2001 | 2nd edition
Crc Press Inc (Verlag)
9780824705435 (ISBN)
CHF 249,95 inkl. MwSt
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Offers an overview of chronic lymphocytic leukemia (CLL) from multiple perspectives. This book chronicles the history and variations of CLL-type leukemia. It reviews the origin, nature, and molecular differences between B-CLL and T-CLL/PLL leukemias. It is for oncologists, hematologists, immunologists, pathologists, internists, and others.
Written by over 50 internationally distinguished experts, 30 more than the first edition, and contains nine new chapters!

Continuing in the esteemed tradition and heralded success of the first edition, Chronic Lymphoid Leukemias, Second Edition offers a full overview of chronic lymphocytic leukemia (CLL) from multiple perspectives-covering all major developments since the previous edition was published eight years ago.

Chronicling the complete history and variations of CLL-type leukemia, the Second Edition

reviews the origin, nature, and molecular differences between B-CLL and T-CLL/PLL leukemias

analyzes core constituents of apoptosis and causes for dysregulation of programmed cell death (PCD) in B-CLL

examines recent research on the role cytokines and regulatory molecules may play in cross-cell communication

profiles commonly used vectors for somatic gene therapy, as well as the latest advances in genetic engineering and vector design and production

utilizes up-to-the-minute techniques such as fluorescence in-situ hybridization (FISH) and comparative genomic hybridization (CGH) to detect genetic abnormalities and aberrations

explores current measures of supportive care with splenectomy, cytokine proteins, and intravenous immunoglobulin applications

identifies how to manage infectious and psychiatric complications in patients with CLL

and much more!
Provides contemporary results on the efficacy of nucleoside analog combinations such as ara-C with fludarabine and cladribine and on the emerging nucleosides nelarabine and clofarabine!

Copiously supplemented with over 2500 literature references-1000 more than the first edition-Chronic Lymphoid Leukemias, Second Edition fulfills the reference needs of oncologists, hematologists, immunologists, pathologists, infectious disease specialists, internists, molecular biologists, and medical school students in these disciplines.

Bruce D. Cheson

History of Chronic Lymphocytic Leukemia
Kanti R. Rai and Tarun Wasil
Molecular Biology of Chronic Lymphocytic Leukemia
Florencia Bullrich and Carlo M. Croce
Chronic Lymphocytic Leukemia: Epidemiological, Familial, and Genetic Aspects
Maria T. Sgambati, Martha S. Linet, and Susan S. Devesa
The Origin and Nature of the Chronic Lymphocytic Leukemia Lymphocyte
Paolo Ghia and Federico Caligaris-Cappio
Immunoglobulin Variable Region Gene Characteristics and Surface Membrane Phenotype Define B-CLL Subgroups with Distinct Clinical Courses
Nicholas Chiorazzi and Manlio Ferrarini
Apoptosis Dysregulation in Chronic Lymphocytic Leukemia
John C. Reed and Shinichi Kitada
Cytokines and Regulatory Molecules in the Pathogenesis and Clinical Course of B-Cell Chronic Lymphocytic Leukemia
Enrica Orsini and Robin Foa
Randomized Trials: What Do They Teach us About Chronic Lymphocytic Leukemia Treatment?
G. Dighiero
Genetic Approaches to the Therapy of Chronic Lymphocytic Leukemia
Thomas J. Kipps
Combination Strategies for Purine Nucleoside Analogs
Varsha Gandhi and William Plunkett
Differential Diagnosis of the Chronic B-Cell Lymphoid Leukemias
Randy D. Gascoyne
Prognostic Factors in Chronic Lymphocytic Leukemia
Stefano Molica
Initial Approach to the Patient with Chronic Lymphocytic Leukemia
Bruce D. Cheson
Management of the Patient with Relapsed or Refractory Chronic Lymphocytic Leukemia
Deborah A. Thomas, Susan M. O'Brien, and Michael J. Keating
The Use of Therapeutic Monoclonal Antibodies in Chronic Lymphocytic Leukemia
Martin J. S. Dyer and Anders Österborg
Genomic Aberrations in B-Cell Chronic Lymphocytic Leukemia
Stephan Stilgenbauer, Peter Lichter, and Hartmut Döhner
Developing Risk-Adapted Treatment Strategies for Chronic Lymphocytic Leukemia
Emilio Montserrat
High-Dose Therapy and Stem Cell Support in Chronic Lymphocytic Leukemia
Angela M. Krackhardt and John G. Gribben
Finding New Therapies for Patients with Chronic Lymphocytic Leukemia
John C. Byrd and Michael R. Grever
Autoimmune Disease and Its Management in Chronic Lymphocytic Leukemia
Terry Hamblin
Richter's Syndrome
John Seymour and Janine Campbell
Supportive Care in Chronic Lymphocytic Leukemia
Farhad Ravandi, Michael J. Keating, and Susan M. O'Brien
Infections in Patients with Chronic Lymphocytic Leukemia: Pathogenesis, Spectrum, and Therapeutic Approaches
Vicki A. Morrison
Prolymphocytic Leukemia of B- and T-Cell Types: Biology and Therapy
Estella Matutes, Vasantha Brito-Babapulle, Claire Dearden, M. R. Yullie, and Daniel Catovsky
Chronic T-Cell and NK-Cell Leukemias
Edgar G. Miranda and Thomas P. Loughran, Jr.
Current Concepts in the Management of Hairy Cell Leukemia
Martin S. Tallman, Mark A. Hoffman, and LoAnn C. Peterson
Psychological Aspects of Chronic Lymphoid Leukemia
Jahandar Saifollahi, Marjaneh Rouhani, Andrew J. Roth, and Jimmie C. Holland

Reihe/Serie Basic and Clinical Oncology
Verlagsort Bosa Roca
Sprache englisch
Maße 210 x 280 mm
Gewicht 1315 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
ISBN-13 9780824705435 / 9780824705435
Zustand Neuware
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