The Inconstant Gene

Lawrence Dillon (Autor)

Buch | Softcover

581 Seiten

2013 | Softcover reprint of the original 1st ed. 1983
Springer-Verlag New York Inc.
978-1-4684-4312-7 (ISBN)

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Why should the gene be suggested to be inconstant when the contrary view, that gene structure is invariant except through mutagenic processes induced by potent external factors, has long been a universal doctrine of genetics? Indeed, during the early part of the present century before mutation was recognized as being of general occurrence, the seeming unvarying nature of the gene led to skepticism regarding the validity of the evolutionary theory; only later could the origins of the morphological differences between individuals and species be attributed to a combination of mutation and evolution, involving natural forces selecting between favorable and unfavorable genetic changes. But during the past several decades, as knowledge of the macromolecular constitution of or ganisms has increased to the point where even the primary structures of the genes themselves are being revealed on a routine basis, it has become increas ingly difficult to ascribe all the resulting observations to ordinary mutagenesis and natural selection. Some more profound mechanism often seems to be present that influences both the constancy and inconstancy of the genes, an ap paratus whose existence this study hopes to reveal. In seeking to demonstrate the universality of this mechanism, data are sought through the numerous activities of organisms of many types wherever gene action changes are manifest.

1. Gene Action Changes in Gametogenesis.- 2. Gene Action Changes during Fertilization.- 3. Gene Action Changes during Early Embryogenesis.- 4. Gene Action Changes during Vertebrate Differentiation.- 5. Gene Action Changes during Nonvertebrate Differentiation.- 6. Gene Expression Changes in Cyclic Functions.- 7. Gene Action Changes in Immunity.- 8. The Nature of The Genetic Mechanism.- References.

Zusatzinfo	240 Illustrations, black and white; VIII, 581 p. 240 illus.
Verlagsort	New York, NY
Sprache	englisch
Maße	152 x 229 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
ISBN-10	1-4684-4312-7 / 1468443127
ISBN-13	978-1-4684-4312-7 / 9781468443127
Zustand	Neuware