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Designs for Clinical Trials -

Designs for Clinical Trials

Perspectives on Current Issues

David Harrington (Herausgeber)

Buch | Softcover
206 Seiten
2013
Springer-Verlag New York Inc.
978-1-4614-2953-1 (ISBN)
CHF 224,65 inkl. MwSt
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This book will examine current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, the design of studies in which missing data is anticipated.  Each chapter will be written by an expert conducting research in the topic of that chapter.  As a collection, the chapters would be intended to serve as a guidance for statisticians designing trials.

New designs for phase I dose finding studies.- Phase II/III designs for trials.- Design issues for clinical studies with genomic measurements.- Designing studies with longitudinal measurements subject to dropout.- Issues in sample size re-estimation.- Adaptive designs.- The design of non-inferiority trials.- Issues in the design of HIV prevention trials.- Randomization algorithms.- Sequential designs for phase III studies.- Case studies of difficult designs.- Ethical issues in the design of trials.- Index.

Reihe/Serie Applied Bioinformatics and Biostatistics in Cancer Research
Zusatzinfo XIV, 206 p.
Verlagsort New York, NY
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Studium
ISBN-10 1-4614-2953-6 / 1461429536
ISBN-13 978-1-4614-2953-1 / 9781461429531
Zustand Neuware
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