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PET and SPECT of Neurobiological Systems

Buch | Hardcover
XVIII, 818 Seiten
2014 | 2014
Springer Berlin (Verlag)
978-3-642-42013-9 (ISBN)
CHF 449,35 inkl. MwSt
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With the latest results in probe development, this volume adopts a multidisciplinary approach in addressing a variety of aspects of neurotransmission in the brain, including visualization and quantification of more than 20 different neuroreceptors.

PET and SPECT of Neurobiological Systems combine the expertise of authors internationally renowned for their dedication to the development of novel probes and techniques for the investigation of neurobiological systems. Various aspects of neurotransmission in the brain are discussed, such as visualization and quantification of neuroreceptors, neuroinflammatory markers, transporters and enzymes as well as neurotransmitter synthesis, beta-amyloid deposition, cerebral blood flow and the metabolic rate of glucose. The latest results in probe development are also detailed. Most chapters are written jointly by radiochemists and nuclear medicine specialists to ensure a multidisciplinary approach. This state-of-the-art compendium will be valuable to all with an interest in the field of clinical or preclinical neuroscience. Other volumes focus on PET and SPECT in psychiatry and PET and SPECT in neurology".

Der Freiburger Musiker und Arzt Andreas Otte studierte und promovierte im Fach Humanmedizin an der Albert-Ludwigs-Universität Freiburg und spezialisierte sich 1999 zum Facharzt für Nuklearmedizin. Er ist gleichzeitig Gitarrist und Gewinner zahlreicher Musikwettbewerbe. Nach der Facharztweiterbildung war Otte über viele Jahre hinweg in leitenden Positionen der klinischen Forschung tätig; darüber hinaus war er 2002 - 2009 Visiting Professor an der Medizinischen Fakultät der Universität Gent in Belgien. Seit 2010 ist Andreas Otte Professor für Biomedizinische Systemtechnik im Studiengang Medizintechnik an der Hochschule Offenburg. Von Andreas Otte sind zahlreiche medizinisch-wissenschaftliche Bücher und Aufsätze - darunter auch musikermedizinische - veröffentlicht sowie einige seiner neoromantischen Kompositionen für Gitarre solo.

BASICS: Animal Models for Brain Research.- Cerebral Glucose Metabolism.- Cerebral Blood Flow Measurements with Oxygen-15 Water PET.- Principles of Brain Perfusion SPECT.- The Impact of Genetic Polymorphisms on Neuroreceptor Imaging.- SYSTEMS: Imaging of Adenosine Receptors.- PET Tracers for Beta-Amyloid and Other Proteinopathies.- Imaging of Central Benzodiazepine Receptors in Chronic Cerebral Ischemia.- PET and SPECT Imaging of the Central Dopamine System in Humans.- PET Imaging of Endocannabinoid System.- Imaging Type 1 Glycine Transporters in the Central Nervous System Using PET.- Imaging Histamine Receptors Using PET and SPECT.- PET and SPECT Imaging of Brain Steroid Hormone Receptors.- Current Radioligands for the PET Imaging of Metabotropic Glutamate Receptors.- PET Imaging of Muscarinic Receptors.- Preclinical Aspects of Nicotinic Acetylcholine Receptor Imaging.- Development of Radioligands for In Vivo Imaging of NMDA Receptors.- Progress in PET Imaging of the Norepinephrine Transporter System.- PET Imaging of Opioid Receptors.- PET Imaging of ABC Transporters in the Blood-Brain Barrier.- PET Imaging of Translocator Protein Expression in Neurological Disorders.- Imaging of the Serotonin System: Radiotracers and Applications in Memory Disorders.- Serotonin Synthesis Studied with PET.- Monoamine Oxidase A and Serotonin Transporter Imaging with PÉT.- PET Imaging of Sigma-1 Receptors.- Radioligands for Imaging Vesicular Monoamine Transporters.

"This is the best comprehensive reference regarding the Functional Imaging of Neurosystems including neurological and psychiatric disorders. ... I recommend this reference and nuclear medicine review book for radiologists and researchers. Scientists in PET research will also benefit from the A-z approaches." (Joseph J. Grenier, Amazon.com, June, 2015)

"This volume explores in detail the most important aspects of the functioning brain ... . The book is therefore ardently suggested to a wide audience represented by all those who work in neurosciences, such as neurologists, psychiatrists, geriatricians, nuclear physicians, neuroradiologists, psychologists and so on; the book could also be interesting for practitioners and basic researchers; finally, representing a strong stimulus to intelligence, it is suggested to all students who want to acquire advanced bases on neuroimaging ... ." (Gianluca de Matteis and Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 42, 2015)

Erscheint lt. Verlag 26.2.2014
Zusatzinfo XVIII, 818 p. 282 illus., 108 illus. in color. With Guest-Editor: Luiten, Paul G.M..
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 1287 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Nuklearmedizin
Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Radiologie
Schlagworte In Vivo Quantification • Nuclear Medicine • radiochemistry
ISBN-10 3-642-42013-3 / 3642420133
ISBN-13 978-3-642-42013-9 / 9783642420139
Zustand Neuware
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