Hallelujah Moments
Oxford University Press Inc (Verlag)
978-0-19-933714-9 (ISBN)
Pharmeceutical drug discovery has wide-reaching and obvious effects on the lives of people everywhere, and yet the general public knows very little about the way in which these important products are conceived. We rely on pharmaceuticals to keep us healthy in countless ways, with almost no understanding of the process behind the creation of the drugs we use. in Hallelujah Moments, Eugene Cordes reveals just how some of the most important and influential drugs are made. He shares his firsthand knowledge of the drug-discovery world, having spent a long and distinguished career on both the academic and industrial side of pharmaceutical research. These tales are "adventure stories," and they follow important drugs like Proscar, Capoten, and Mevacor from the idea stage all the way to the point of being made publicly available. Cordes shows us the dynamic and critical thinking needed to create a useful drug, and the human stories of risk-taking, problem-solving, and, in many cases, failure. Written accessibly for a non-scientist audience, Hallelujah Moments brings the general public up to speed on the fascinating world of drug discovery like never before.
Dr. Eugene Cordes has been a professor at the University of Michigan since 1995. In addition to having served as Vice President at Merck Research Laboratories and as the Vice President of R&D at Eastman Pharmaceuticals, he is the author of The Tao of Chemistry and Life (OUP 2009).
Table of Contents ; Chapter 1: Seduced by drug discovery ; Chapter 2: The small molecules of life ; Chapter 3: Proteins: molecular wonders in three dimensions ; Chapter 4. Proteins perform multiple functions: enzymes, receptors, ion channels ; Chapter 5: Drug discovery and development: the road from an idea to promoting ; human health ; Chapter 6: Finasteride: the Gary and Jerry show ; Chapter 7: Basic research, snake venoms, and ACE inhibitors: Ondetti, Cushman, and ; Patchett ; Chapter 8: Statins: protection against heart attacks and strokes ; Chapter 9: The perils of Primaxin ; Chapter 10: Avermectins: molecules of life battle parasites ; Chapter 11: Fludalanine: nice try but no hallelujah ; Chapter 12: Diabetes Breakthrough: Januvia and Janumet
| Erscheint lt. Verlag | 13.3.2014 |
|---|---|
| Zusatzinfo | 28 halftone, 26 line art |
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 236 x 163 mm |
| Gewicht | 522 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
| Medizin / Pharmazie ► Pflege | |
| ISBN-10 | 0-19-933714-4 / 0199337144 |
| ISBN-13 | 978-0-19-933714-9 / 9780199337149 |
| Zustand | Neuware |
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