Disease-modifying Therapy in Vasculitides

Cees G.M. Kallenberg, Jan W. Cohen Tervaert (Herausgeber)

Buch | Softcover

IX, 206 Seiten

2012 | Softcover reprint of the original 1st ed. 2001
Springer Basel (Verlag)
978-3-0348-9485-2 (ISBN)

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Especially the past two decades have seen renewed interest in thevasculitides. In this volume an international expert group presents thecurrent state of knowledge and concentrates on principles of immunemodulating therapy. Drawing from their work in rheumatology, nephrology,internal medicine, connective tissue disease and clinical immunology,they present new concepts in classificiation, diagnosis andpathophysiology of the vasculitides. Evidence from experimental andclinical trials is reviewed, as well as the outlook for furtherresearch.

Systemic vasculitides, an introduction.- Standard therapeutic regimens for vasculitis.- Tumor necrosis factor (TNF) inhibition in the treatment of vasculitis.- Methotrexate as an alternative to classic immunosuppressive therapies.- Intravenous immunoglobulin as immuno-modifying treatment.- T-cell directed treatment: anti-thymocyte globulin.- New immunosuppressants: mycophenolate mofetil and 15-deoxyspergualin.- Interferon-? for the treatment of virus-related systemic vasculitides.- Autologous stem cell therapy for systemic vasculitis.- Prevention of relapsing disease in anti-neutrophil cytoplasmic antibody related necrotizing small-vessel vasculitis: the role for autoantibody guided and anti-bacterial treatment.

Erscheint lt. Verlag	23.10.2012
Reihe/Serie	Progress in Inflammation Research
Zusatzinfo	IX, 206 p.
Verlagsort	Basel
Sprache	englisch
Maße	155 x 235 mm
Gewicht	339 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete
Themenwelt	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
Schlagworte	Bacteria • clinical trial • Immunoglobulin • immunology • Interferon • Internal Medicine • necrosis • pathophysiology • Physiology • prevention • Tumor
ISBN-10	3-0348-9485-6 / 3034894856
ISBN-13	978-3-0348-9485-2 / 9783034894852
Zustand	Neuware