Mediators of Sepsis

Maurice Lamy, Lambert G. Thijs (Herausgeber)

Buch | Softcover

XIV, 414 Seiten

2012 | 1. Softcover reprint of the original 1st ed. 1992
Springer Berlin (Verlag)
978-3-642-84829-2 (ISBN)

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This volume contains contributions by well-known scientistsand clinicians in the fields of microbiology, infectiousdiseases, physiology, internal medicine, surgery,anaesthesiology, and intensive care medicine.It provides an up-to-date overview of the mediators andpathophysology of sepsis and septic shock as well as thelatest therapeutic approaches.

Mediators and Pathophysiology of Sepsis.- Sepsis and Multiple Organ Failure: Consensus and Controversy.- Endotoxin Administration to Humans: A Model of Inflammatory Responses Relevant to Sepsis.- Mediators of Lung Injury Following Ischemia and Reperfusion.- Cytokines in Shock: 1992.- TNF-? and Soluble TNF Receptors in Meningococcemia.- Role of the Complement Cascade in Severe Sepsis.- The Role of the Kallikrein-Kinin System in Septic Shock.- The Procoagulant State in Sepsis: Experimental Models and New Modalities for Intervention.- Leukocyte-Endothelial Interactions in Trauma and Sepsis.- Oxyradical Pathogenesis in Sepsis.- PAF, Cytokines and Cell to Cell Interactions in Shock and Sepsis.- Nitric Oxide as a Mediator of the Vascular Derangements of Sepsis and Endotoxemia.- Endogenous Opioids and Opioids Antagonists in Endotoxic and Septic Shock: A Current Perspective.- Role of Neural Stimuli and Pain.- Sepsis and Strenuous Exercise: Common Inflammatory Factors.- The Gut-Liver Axis in Multiple Organ Failure.- Secondary Hepatic Dysfunction: Clinical Epidemiology, Pathogenesis and Current Therapeutic Approaches.- Cardiac Effects of the Mediators of Sepsis.- The Peripheral Vasculature.- New Therapeutic Approaches to Sepsis.- Dilemmas in Sepsis Clinical Trials Design and Analysis.- Experimental Basis of New Therapeutic Approaches to Septic Shock.- Anti-Endotoxin Antibodies: A Critical Appraisal.- The Case for Immunotherapy Against Endotoxin in Sepsis and Septicemia.- Bactericidal Permeability Increasing Protein: A Potent Naturally Occurring Anti-Endotoxin Protein.- Strategies for Modulation of Systemic and Tissue Cytokine Responses to Sepsis.- Blocking Cytokines in Infectious Diseases.- Platelet Activating Factor: Rationale for the Use of PAF-Antagonists in Sepsis.- MediatorGene Expression in Sepsis: Implications for Therapy.

Erscheint lt. Verlag	9.2.2012
Reihe/Serie	Update in Intensive Care and Emergency Medicine
Zusatzinfo	XIV, 414 p.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Gewicht	650 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Chirurgie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Intensivmedizin
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Notfallmedizin
Schlagworte	ant-endotoxin-antibodies • Anti-Endotoxin-Antikörper • Care • complement-cascade • endotoxic shock • endotoxischer Schock • Infectious Diseases • Intensive care • Intensive Care Medicine • Komplement-Kaskade • Physiology • Sepsis • Septic shock • Septischer Schock • shock • Surgery • TNF-Receptors • TNF-Rezeptoren
ISBN-10	3-642-84829-X / 364284829X
ISBN-13	978-3-642-84829-2 / 9783642848292
Zustand	Neuware