Hormonally Active Brain Peptides

Structure and Function

Kenneth W. McKerns, Vladimir Panti? (Autoren)

Buch | Softcover

640 Seiten

2013 | Softcover reprint of the original 1st ed. 1982
Springer-Verlag New York Inc.
978-1-4615-9250-1 (ISBN)

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Near the end of September 1980, the contributors to Hormonally Active Brain Pep tides: Structure and Function met to discuss their chapters for the monograph. This meeting was the eighth sponsored by the International Foundation for Biochemical Endocrinology and was held at the Hotel Plakir in Dubrovnik, Yugoslavia. Several months were allowed after the meeting for the contributors to revise their manuscripts and for editing. Professor Dr. Vladimir Pantie and the Serbian Academy of Sciences and Arts were in charge of the local arrangements and social activities. The Foundation is grateful for the splendid job that was done and for the out- standing scientific, cultural, and social activities. I thank the Serbian Acad- emy of Sciences and Arts and the Yugoslav Council of Academies for spon- soring my stay in Yugoslavia. I greatly enjoyed giving lectures, visiting laboratories, and discussing research projects in a number of centers in Yugoslavia. A diverse group of topics was presented in Dubrovnik concerning cer- tain brain peptides.
The topics included "Structure, Function, and Confor- mation of Neuropeptides," "Distribution of Peptides in the Brain," "Reg- ulation of the Release of Peptide Hormones," "The Active Center of Gonadotropins," "In Vitro Synthesis of Hypothalamic Hormones," "Stud- ies on Gonadotropin-Releasing Hormone," "Studies on the Biosynthesis, Release, and Degradation of LH-RH," "Genesis and Properties of Pitu- itary ACTH, Prolactin, and Growth Hormone Producing Cells," "Precur- sors to Oligopeptide Hormones," and "Stress Effects on Peptide Hormone Synthesis.

1 Structure and Function Relationships among Synthetic Enkephalin Analogues.- 2 Secondary Structure — Function Relationships in ?-Endorphin: A Proposed Model of the Biologically Active Conformation.- 3 Studies on the Conformation of Neuropeptides.- 4 The Search for the Active Center of the Gonadotropins.- 5 Hormonal Antagonistic Properties of Deglycosylated Pituitary Lutropin.- 6 Hormonal Regulation of and Ionic Requirements for in Vitro Release of Hypothalamic Peptides.- 7 In Vitro Release of Luteinizing Hormone-Releasing Hormone: Influence of Estrogen and a Mammary Carcinogen.- 8 Mode of Opioid and Catecholamine Involvement in Regulating LH Secretion.- 9 Stress, Corticoliberin (CRF), and Glucocorticoids in the Regulations of ACTH Release.- 10 The Role of Steroid Receptors in the Regulation and Integration of Steroid and Peptide Hormone Actions in Common Target Cells: Facts and Speculations.- 11 Effects of Estrogens on Receptor “Nucleotropy” and “Activation”.- 12 Steroids and Membrane-Associated Events in Neurons and Pituitary Cells.- 13 Electrical Effects of Steroids in Neurons.- 14 Recent Data on Neuropeptide Mapping in the Central Nervous System.- 15 Distribution and Changes in Peptides in the Brain.- 16 In Vitro Synthesis of Hypothalamic Neurophysin Precursors.- 17 Steroid Antagonism of Melanosome Movements Induced by Neuropeptides.- 18 Is VIP a Neuroregulator or a Hormone?.- 19 Gonadotropin-Releasing Hormone: Release into Hypophyseal Portal Blood and Mechanism of Action.- 20 Biodegradation of Luteinizing Hormone-Releasing Hormone.- 21 Ultrastructural Characteristics of Proteinergic Synthesis in the Pineal Gland.- 22 Peptidergic Activity of the Pineal Gland in Stress.- 23 Effect of Colchicine on the Stress-Type ACTH Release in Rats.- 24 Genesis andProperties of Pituitary ACTH, MSH, Prolactin, and GH Producing Cells.- 25 Interaction between Thyrotropin-Releasing Hormone and Prolactin-Producing Cells.- 26 Cell-Free Synthesis of Rat Lutropin Subunits.- 27 Cellular Polyproteins from Pituitary and Hypothalamus: Composite Precursors to Oligopeptide Hormones.- 28 Tritium Labeling of Brain Peptides.- Appendix Members of the International Foundation for Biochemical Endocrinology.

Reihe/Serie	Biochemical Endocrinology
Zusatzinfo	155 Illustrations, black and white; XVII, 640 p. 155 illus.
Verlagsort	New York, NY
Sprache	englisch
Maße	152 x 229 mm
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	1-4615-9250-X / 146159250X
ISBN-13	978-1-4615-9250-1 / 9781461592501
Zustand	Neuware