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Phosphoinositides in Subcellular Targeting and Enzyme Activation -

Phosphoinositides in Subcellular Targeting and Enzyme Activation

Harald Stenmark (Herausgeber)

Buch | Softcover
IX, 209 Seiten
2012 | Softcover reprint of the original 1st ed. 2004
Springer Berlin (Verlag)
978-3-642-62299-1 (ISBN)
CHF 179,70 inkl. MwSt
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Cells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.

List of Contents.- Phosphoinositide Involvement in Phagocytosis and Phagosome Maturation.- Regulation of Endocytosis by Phosphatidylinositol 4,5-Biphosphate and ENTH Proteins.- Membrane Targeting by Pleckstrin Homology Domains.- Protein Targeting to Endosomes and Phagosomes via FYVE and PX Domains.- Regulation of the Actin Cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3.- Roles of PI3K in Neutrophil Function.- Nuclear Phosphoinositides and Their Functions.

From the reviews:

"The book consists of seven chapters that focus on the various functions of PtdIns. ... summarises recent advances in the burgeoning field of inositol lipids and provides a snapshot of where the field stands in 2003. The field is moving rapidly but this volume will be a useful addition for many researchers who have only recently discovered that their favourite protein is regulated by PtdIns." (Shamshad Cockcroft, nature cell biology, Vol. 6 (6), June, 2004)

Erscheint lt. Verlag 16.12.2012
Reihe/Serie Current Topics in Microbiology and Immunology
Zusatzinfo IX, 209 p.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 352 g
Themenwelt Studium Querschnittsbereiche Infektiologie / Immunologie
Schlagworte Chemotaxis • endocytosis • Microorganism • phagocytosis • phosphoinositide • Protein • proteins • signal transduction
ISBN-10 3-642-62299-2 / 3642622992
ISBN-13 978-3-642-62299-1 / 9783642622991
Zustand Neuware
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