Pathobiology of the Human Atherosclerotic Plaque

Seymour Glagov, William P. Newman III, Sheldon A. Schaffer (Herausgeber)

Buch | Softcover

923 Seiten

2011 | Softcover reprint of the original 1st ed. 1990
Springer-Verlag New York Inc.
978-1-4612-7968-6 (ISBN)

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Seymour Glagov The last meeting, devoted exclusively to an examination of the atherosclerotic plaque, took place in Chicago 25 years ago under the joint auspices of the Council on Arteriosclerosis of the American Heart Association and the Chicago Heart Association. The proceedings were published subsequently in a volume entitled "Evolution of the Atherosclerotic Plaque", edited by Richard J. Jones (1). Both experimental and human lesions were considered and several provocative new approaches to the disorder were discussed. The electron microscope was being applied systematically to the study of blood vessels at that time, so that details of the infrastructure and cellular composition of the artery wall and of atherosclerotic lesions were presented in some detail. There was, as one result of these explorations, considerable discussion of morphologic evidence suggesting that the principal cell involved in the atherogenic process was neither the fibroblast nor the macrophage, as had been supposed, but the smooth muscle cell. In particular, the findings indicated that this cell could incorporate lipid and become a foam cell.

Cellular Contents.- Tissue Organization and Architecture.- Pathobiologic Processes.- Response of Human Lesions to Direct Intervention and Risk Factor Control.- Evaluation of Lesion Status in Major Arterial Beds.- Current and Prospective Methods for Detecting Plaque Change.- Summary.

Zusatzinfo	XXXI, 923 p.
Verlagsort	New York, NY
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
Schlagworte	Artherienverkalkung • Pathologie
ISBN-10	1-4612-7968-2 / 1461279682
ISBN-13	978-1-4612-7968-6 / 9781461279686
Zustand	Neuware