Advances in Cardiomyopathies

G. Baroldi, F. Camerini, J.F. Goodwin (Herausgeber)

Buch | Softcover

XVII, 480 Seiten

2012 | 1. Softcover reprint of the original 1st ed. 1990
Springer Berlin (Verlag)
978-3-642-83762-3 (ISBN)

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The international symposium organized by the Italian Study Group on Cardiomyopathies (SPIC) and planned by the organiz ing and scientific committees opened with a review of the history of cardiomyopathy over the last 30 years by Goodwin, London (UK) and continued with presentations on all aspects of hyper trophic and dilated cardiomyopathy by a wide spectrum of inter national experts. This book includes mainly the invited contributions, but there are also many original oral presentations. Hypertrophic cardiomyopathy is well addressed by papers on natural history, ventricular function, ischaemia and arrhythmia. Of particular interest is the note by Bonow, National Heart Lung and Blood Institute (NHLBI; USA), on the effect of beta-adrenergic stimulation with isoprenalin in increasing the rate and extent of left ventricular relaxation, beta-adrenergic blocking agents having no such effect. In contrast, verapamil improves ventricular relaxation as would be expected. These results challenge accepted belief in some ways and indicate that multiple factors - both passive and active - acting on the left ventricle, such as ischaemia, asynchrony, altered left ventricu lar loading and intracellular levels of calcium ions, are all oper ating. These aspects are the more interesting in view of the recent reports of an increase in calcium-channel receptors, but not in beta-adrenergic receptors, in hypertrophic cardiomyo pathy.

International contributions with latest advances. The editors are well known all over the world as leading authorities in the field.

Introduction: Thirty Years of Cardiomyopathy.- I Hypertrophic Cardiomyopathy.- Evolution of Left Ventricular Hypertrophy in Patients with Hypertrophic Cardiomyopathy.- The Natural History and Clinical Course of Hypertrophic Cardiomyopathy.- Left Ventricular Systolic and Diastolic Function in Hypertrophic Cardiomyopathy.- Radionuclide Assessment of Diastolic Function in Hypertrophic Cardiomyopathy: Relation to Symptoms and Prognosis.- Ischemia, Coronary Blood Flow, and Coronary Reserve in Hypertrophic Cardiomyopathy.- Left Ventricular Diastolic Function and Myocardial Ischemia in Hypertrophic Cardiomyopathy: Assessment by Radionuclide Methods.- Sudden Death in Hypertrophic Cardiomyopathy: Identification and Management of High Risk Patients.- Electrophysiologic Studies in Patients with Hypertrophic Cardiomyopathy: Safety and Relation of Results to Clinical Findings.- Cerebral Embolic Risk in Hypertrophic Cardiomyopathy.- Cytogenetic Studies in Familial Hypertrophic Cardiomyopathy: Identification of a Fragile Site on Human Chromosome 16.- Medical Treatment of Hypertrophic Cardiomyopathy.- Surgical Results in Patients with Hypertrophic Obstructive Cardiomyopathy.- Utility of Intraoperative Echocardiography in Planning Surgical Strategy in Obstructive Hypertrophic Cardiomyopathy.- Rational Choice of Medical and/or Surgical Therapy in Hypertrophic Cardiomyopathy.- Changes in Left Ventricular Hemodynamics of Hypertrophic Obstructive Cardiomyopathy (HOCM) Patients Treated with VAT Sequential Pacing.- Future Trends in Research in Hypertrophic Cardiomyopathy.- II Dilated Cardiomyopathy.- 1 Pathogenesis of Dilated Cardiomyopathy.- Experimental Viral Myocarditis: Immunopathogenetic Aspects.- Dichotomous Effects of Cyclophosphamide in Murine Coxsackievirus B3-Induced Myocarditis.- Enterovirus RNA Sequences in Hearts with Dilated Cardiomyopathy: A Pathogenetic Link Between Virus Infection and Dilated Cardiomyopathy.- HLA Haplotype in Idiopathic Dilated Cardiomyopathy: Genetically Determined Immune Response Factors of Etiologic Importance?.- Humoral and Cell-Mediated Immunity: Pathogenetic Mechanisms in Dilated Cardiomyopathy.- Biomolecular Changes in Dilated Cardiomyopathy.- The ?-Adrenergic Receptor-G Protein-Adenylate Cyclase Complex in Idiopathic Dilated Cardiomyopathy.- Immune-Genetic Control of Anti-?-Receptor Antibodies in Human Idiopathic Dilated Cardiomyopathy.- Catecholamines, ?-Receptors and Morphology in Dilated Cardiomyopathy: A Preliminary Report.- 2 Morphology of Dilated Cardiomyopathy.- Histopathological Diagnosis of Acute Myocarditis and Dilated Cardiomyopathy.- Ultrastructural Changes in Myocarditis and Dilated Cardiomyopathy.- Diagnostic and Prognostic Value of Immunofluorescence and Electron-Microscopic Findings in Idiopathic Dilated Cardiomyopathy.- 3 Clinical Aspects and Treatment of Myocarditis.- Natural History of Viral Myocarditis: Critical Viewpoints.- Clinical Presentation and Evolution in Treated and Untreated Myocarditis.- Immunosuppressive Therapy in Active Myocarditis.- Immunosuppressive Therapy in Myocarditis - 24-Month Follow-up.- 4 Clinical Aspects of Dilated Cardiomyopathy.- Natural History and Prognosis of Overt Dilated Cardiomyopathy.- Myocardial Perfusion and Metabolism in Dilated Cardiomyopathy.- Complex Ventricular Arrhythmias in Dilated Cardiomyopathy: A Multicenter Italian Experience.- Essential Ventricular Arrhythmias: An Early Step Toward Cardiomyopathy?.- Role of Radionuclide Angiography in the Diagnosis of Early Ventricular Dysfunction in Patients with Complex Ventricular Arrhythmias.- ItalianMulticenter Cardiomyopathy Study Group.- Dilated Cardiomyopathy in Children.- Anatomoclinical Aspects of Arrhythmogenic Right Ventricular Cardiomyopathy.- Right Ventricular Arrhythmogenic Cardiomyopathy: The Clinical Point of View.- Arrhythmologic Study in Arrhythmogenic Right Ventricular Dysplasia: Prognostic Implications in Fifty Patients.- 5 Treatment of Dilated Cardiomyopathy.- Positive Inotropic Therapy for Chronic Dilated Cardiomyopathy and Congestive Failure.- Vasodilator Therapy for Cardiomyopathy.- Beta-Blockade in Dilated Cardiomyopathy.- Role of Antiarrhythmic Treatment in Dilated Cardiomyopathy.- Cardiac Transplantation for Dilated Cardiomyopathy.- Long-Term Treatment with Amiodarone for the Prevention of Sudden Death in Patients with Dilated Cardiomyopathy.

Erscheint lt. Verlag	22.1.2012
Zusatzinfo	XVII, 480 p.
Verlagsort	Berlin
Sprache	englisch
Maße	170 x 242 mm
Gewicht	854 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie
Schlagworte	Angiography • Antiarrhythmic treatment • Arrhythmia • Catecholamines • Echocardiography • heart • Heart Transplantation • hemodynamics • Hypertrophic/Dilated Cardiomyopathy • Morphology • sudden cardiac death • Transplantation
ISBN-10	3-642-83762-X / 364283762X
ISBN-13	978-3-642-83762-3 / 9783642837623
Zustand	Neuware