Toxicology of Insecticides

Fumio Matsumura (Autor)

Buch | Softcover

504 Seiten

2011 | Softcover reprint of the original 1st ed. 1975
Springer-Verlag New York Inc.
978-1-4613-4412-4 (ISBN)

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Why are books written? Since I have read many works by my colleagues with admiration, this question has always intrigued me. Further, writing a book takes a good deal of time and effort, and I had imagined that I would never undertake such a demanding task. A few unexpected events and circumstances have changed my mind. The first was the pleasant experience of editing Environmental Toxicology of Pesticides with Drs. Mallory Boush and Tomomasa Misato. This fine symposium volume occasioned many interesting responses, including a suggestion to prepare a more complete treatise on the grounds that such "proceedings" volumes, by their very nature, do not satisfactorily offer a complete and coherent description of the field, but cater chiefly to specialists. I myself prefer single-authored books for basic understanding of a scientific field. The second circumstance leading to the present volume was the avail ability of teaching notes from my course on the toxicology of insecticides. As the need to cultivate environmental awareness has increased, there has been a parallel increase in the enrolments of such courses both here and in other major institutions. Yet no comprehensive and up-to-date text has been available. The third factor which facilitated the effort was an especially pleasant sabbatical in Hawaii, where the availability of the excellent Hamilton Library at the University of Hawaii considerably eased my task.

1 Introduction.- 1.1. Toxicolog.- 1.2. General Patterns of Pesticide Us.- 1.3. Economic and Legal Aspects of Pesticide Us.- 1.4. Reference.- 2 General Principles of Insecticide Toxicology.- 2.1. Evaluation of Toxicity.- 2.2. Analytical Methods for Insecticides.- 2.3. References.- 3 Classification of Insecticides.- 3.1. History and General Groupings of Insecticidal Compounds.- 3.2. Chlorinated Hydrocarbon Insecticides.- 3.3. Organophosphorus Insecticide.- 3.4. Carbamate Insecticides.- 3.5. Thiocyanate Insecticides.- 3.6. Dinitrophenols.- 3.7. Fluoroacetate Derivatives.- 3.8. Acaricidal Chemicals: Sulfonates, Sulfones, Sulfides, and Nitrogen-Containing Compounds.- 3.9. Fumigants.- 3.10. Inorganic Insecticides.- 3.11. Botanical Insecticides.- 3.12. Synergists.- 3.13. References.- 4 Modes of Action of Insecticides.- 4.1. Introduction.- 4.2. Classification of Insecticides by Their Actions.- 4.3. The Nervous System.- 4.4. Chlorinated Hydrocarbon Insecticides.- 4.5. Naturally Occurring Botanical Insecticides.- 4.6. Organofluorine Compounds: Fluoroacetate and Its Analogues.- 4.7. Anticholinesterases: Organophosphorus and Carbamate Insec ticides.- 4.8. Inhibitors of Respiratory Enzymes.- 4.9. Inhibitors of Mixed-Function Oxidases.- 4.10. Chlordimeform and Its Analogues.- 4.11. References.- 5 Metabolism of Insecticides by Animals and Plants.- 5.1. General Types of Metabolic Activities.- 5.2. Primary Metabolic Processes.- 5.3. Conjugation Systems: Secondary Metabolic Processes.- 5.4. Metabolic Reactions Characteristic of Each Group of Insecti- cidal Chemicals.- 5.5. References.- 6 Entry of Insecticides into Animal Systems.- 6.1. Penetration of Insecticides Through the Insect Cuticle.- 6.2. Routes of Insecticide Entry into Insects.- 6.3. Routes of Insecticide Entry into Higher Animals.- 6.4. References.- 7 Dynamics of Insecticide Movement in the Animal Body.- 7.1. Total Intake-Elimination Dynamics.- 7.2. Transport of Insecticides by Blood and Body Fluid.- 7.3. Distribution and Redistribution Within the Animal Body.- 7.4. Factors Affecting Storage and Release.- 7.5. Penetration and Distribution into Vital Organs and Tissues.- 7.6. Elimination of Insecticides: Excretion and Secretion.- 7.7. References.- 8 Movement of Insecticides in the Environment.- 8.1. Introduction.- 8.2. Residues of Insecticides.- 8.3. Movement of Residues in the Environment.- 8.4. References.- 9 Environmental Alteration of Insecticide Residues.- 9.1. Characteristics of Environmental Alteration.- 9.2. Characteristics of Microbial Metabolism.- 9.3. Metabolism of Chlorinated Hydrocarbon Insecticides by Microorganisms.- 9.4. Metabolism of Organophosphate and Carbamate Insecticides by Microorganisms.- 9.5. Metabolism of Acaricidal Compounds by Microorganisms.- 9.6. Degradation by Sunlight and Other Physical Factors.- 9.7. References.- 10 Effects of Pesticides on Wildlife.- 10.1. General Survey of Residue Levels in Various Ecosystems.- 10.2. Hazards to Wildlife.- 10.3. Biological Transfer and Bioaccumulation.- 10.4. References.- 11 Hazards to Man and Domestic Animals.- 11.1. Introduction.- 11.2. Acute Poisoning by Insecticidal Chemicals.- 11.3. Chronic Toxicity and Studies on Subtle Effects.- 11.4. Insecticide Residues in Man.- 11.5. References.- Author Index.

Zusatzinfo	XVIII, 504 p.
Verlagsort	New York, NY
Sprache	englisch
Maße	152 x 229 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Pharmazie
	Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie
	Veterinärmedizin
ISBN-10	1-4613-4412-3 / 1461344123
ISBN-13	978-1-4613-4412-4 / 9781461344124
Zustand	Neuware