Alzheimer's Disease
John Wiley & Sons Ltd (Verlag)
978-0-471-98683-6 (ISBN)
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Alzheimer's disease is an ever-present problem of enormous magnitude affecting every country in the world. A global scientific effort is needed to discover its causes, develop effective treatments and ultimately prevent its occurrence. This volume provides both clinicians and academics with the cutting edge developments in the field. All aspects of Alzheimer's disease are covered, including diagnosis, clinical course, histopathological course, epidemiology, risk factors, molecular genetics, molecular pathology, mechanisms of neurodegeneration, cellular and animal models, related neurodegenerative conditions, therapeutics and psycho-social issues.
Partial table of contents:; EPIDEMIOLOGY AND RISK FACTORS; Time Trends in the Prevalence of Dementia and Alzheimer's Disease in Rochester, Minnesota (E. Kokmen, et al.); Prognosis with Dementia: Results from a European Collaborative Analysis of Population-based Studies (C. Jagger, et al.); GENETIC FACTORS; The Risk of Developing Alzheimer's Disease Associated with the APOE Promoter Polymorphisms (J.-C. Lambert, et al.); Association of Genetic Risk Factors in Alzheimer's Disease and a Novel Mutation in the Predicted TM2 Domain of the Presenilin-2 Gene in Late-onset AD (R. Cacabelos, et al.); DIAGNOSIS, CLINICAL AND HISTOPATHOLOGICAL; Structural Neuroimaging: Early Diagnosis and Staging of Alzheimer's Disease (M. de Leon, et al.); Cerebrospinal Fluid Aspartate Aminotransferase Activity Is Increased in Alzheimer's Disease (T. Tapiola, et al.); MOLECULAR PATHOLOGY; Enrichment of Presenilin 1 Peptides in the Membranes of Neuronal Vesicles: Implications for Alzheimer's Disease (S. Efthimiopoulos, et al.); Molecular Anatomy of Tau Inclusions with Antibodies to Specifically Recognize Tau Isoforms (S. Arawaka, et al.); MECHANISMS OF NEURODEGENERATION; Inhibition of Neurofibrillary Degeneration: A Rational and Promising Therapeutic Target (K. Iqbal, et al.); Role of Presenilin Processing and Caspases for Amyloid -Peptide Generation and NOTCH-Signaling (S. Rvhrig, et al.); Neuro-inflammatory Mechanisms in Alzheimer's Disease (P. McGeer, et al.); -Amyloid-induced Inflammatory Molecular Cascades in Vascular Cells (Z. Suo, et al.); RELATED NEURODEGENERATIVE CONDITIONS; Cracking An Enigma: The Puzzle of Unusual Dementias (P. Lantos); Formation of Protease-resistant Prion Protein In Vitro: Stimulation and Inhibition (B. Caughey, et al.); CELLULAR AND ANIMAL MODELS; hFE65L Over-expression Enhances -Amyloid Precursor Protein Maturation and Processing (S. Guinette, et al.); Monoamine Oxidase Activities in Murine Neuroblastoma Cells upon Acute or Chronic Treatment with Aluminum or Tacrine (P. Zatta & P. Zambenedetti); THERAPEUTICS; Trends in Alzheimer's Disease Treatment and Prevention (F. Forette & F. Boller); CSF Tau Protein Levels Before and After Tacrine Therapy in Patients with Dementia of Alzheimer's Type (M. Tsolaki, et al.); NON-PHARMACOLOGICAL TREATMENTS; Decreased Neuronal Activity and Therapeutic Strategies Directed towards Reactivation in Alzheimer's Disease (D. Swaab, et al.); Exercise Program in Patients with Alzheimer's Disease (C. Mouzakidis, et al.); PSYCHOSOCIAL; The Circle Model Support for Relatives of People with Dementia (W. Jansson, et al.); Development of a Short Measurement of Individual Quality of Life (SEIQoL Short Form) (D. Meier, et al.); Indexes.
| Zusatzinfo | illustrations (some colour) portraits |
|---|---|
| Verlagsort | Chichester |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 1350 g |
| Einbandart | gebunden |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Geriatrie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie | |
| ISBN-10 | 0-471-98683-6 / 0471986836 |
| ISBN-13 | 978-0-471-98683-6 / 9780471986836 |
| Zustand | Neuware |
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