Multiple Myeloma

Thomas Moehler, Hartmut Goldschmidt (Herausgeber)

Buch | Softcover

XXIV, 340 Seiten

2013 | 2011
Springer Berlin (Verlag)
978-3-642-26799-4 (ISBN)

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Multiple myeloma is currently still an incurable disease, but during the past decade knowledge of its molecular pathogenesis has increased rapidly. This has led to remarkable progress in both diagnosis and therapy, including in particular the approval of novel and first-in-class drugs such as thalidomide, bortezomib, and lenalidomide. This book, written by internationally acknowledged experts, covers a wide range of topics relating to multiple myeloma, including history, epidemiology, pathophysiology, clinical features, staging, and prognostic systems. The principal focus, however, is on therapy, with detailed information on the various promising treatment options which give hope that this cancer will be transformed into a chronic disease or even become curable. Individualized therapy and the variety of supportive treatment options, as described in this volume, will help in achieving this goal, as well as in reducing adverse events and improving quality of life.

History and epidemiology.- Pathophysiology: Molecular biology of plasma cell disorders.Alterations in microenvironment.- Clinical Features: Imaging. Integrated innovative approach for diagnosis and staging.- Therapy: High-dose chemotherapy and ABSCT.- Allogeneic transplantation. Novel Drugs.- Immunotherapeutic approaches.- First-line treatment and maintenance.- Relapse.- Radiotherapy.- Kyphoplasty.- Supportive Therapy.- Appendix: Staging and prognosis systems.

Erscheint lt. Verlag	30.5.2013
Reihe/Serie	Recent Results in Cancer Research
Zusatzinfo	XXIV, 340 p.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Gewicht	557 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Hämatologie
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
Schlagworte	ABSCT • kyphoplasty • Plasma cell disorders
ISBN-10	3-642-26799-8 / 3642267998
ISBN-13	978-3-642-26799-4 / 9783642267994
Zustand	Neuware