The Autoimmune Diseases

M. Eric Gershwin, George C. Tsokos (Herausgeber)

Buch | Hardcover

1304 Seiten

2014 | 5th edition
Academic Press Inc (Verlag)
978-0-12-384929-8 (ISBN)

Infos

Incorporates material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. This title discusses the biological basis of disease at genetic, cellular, and epidemiologic levels and includes coverage of autoinflammatory disease and autoimmune responses to tumors.

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Since publication of the 4th Edition of The Autoimmune Diseases in 2006, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This fully revised 5th Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels and includes expanded coverage of autoinflammatory disease and autoimmune responses to tumors.

Autor

M. Eric Gershwin, MD, is chief of the division of rheumatology, allergy, and clinical immunology at the University of California at Davis. Gershwin is currently working to further understand the molecular basis of immune regulation in autoimmunity. He also studies the molecular-genetic basis of autoimmune liver disease. Gershwin is interested in the molecular and genetics tools being utilized to study the genes that contribute to a patient's susceptibility to lupus and the cellular and subcellular mechanisms that lead to immune disease. George C. Tsokos, MD, is a Professor of Medicine at Harvard Medical School and Chief of Rheumatology and Clinical Immunology at Beth Israel Deaconess Medical Center. Dr Tsokos has served as President of the Clinical Immunology Society, on the boards of directors for the American College of Rheumatology and the Lupus Foundation of America, member/chair of multiple federal study sections, and editor/member of the editorial boards for top scientific journals. He has received several awards, including a MERIT from NIH, the Lee C. Howley Sr. Prize, the Evelyn V. Hess, the Distinguished Basic Investigator Award from the American College of Rheumatology, the Lupus Insight Prize from the Lupus Research Alliance, and the Carol Nachman Prize for Rheumatology. He is a Master of the American College of Physicians and the American College of Rheumatology, a member of American Association of Physicians and Fellow of AAAS.

Inhalt

Part I. Immunologic Basis of Autoimmunity

Part II A.Immune Cells and Immune Responses

Part II B. Non-Antigen-Specific Recognition

Part III. Initiation of Autoimmunity

Part IV. Facilitation of Autoimmunity

Part V. Experimental Models of Autoimmunity

Part VI. Multisystem Autoimmune Diseases

Part VII. Endocrine System

Part VIII. Blood Disorders

Part IX. Central and Peripheral Nervous System

Part X. Gastrointestinal System

Part XI. Skin Diseases

Part XII. Nephropathies and Reproductive System

Part XIII. Cardiovascular System and Lungs

Part XIV. Unclassified Expressions of Autoimmunity

Part XV. Diagnosis, Prevention and Therapy

Produkt-Details

• Erscheint lt. Verlag: 30.1.2014
• Verlagsort: San Diego
• Sprache: englisch
• Maße: 216 x 279 mm
• Gewicht: 3210 g
• Themenwelt: Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
• ISBN-10: 0-12-384929-2 / 0123849292
• ISBN-13: 978-0-12-384929-8 / 9780123849298
• Zustand: Neuware