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AlGaN-based pH-sensors : impedance characterisation, optimisation and application for foetal blood sampling

Benedikt Lübbers (Autor)

Buch | Softcover

352 Seiten

2013
TU Ilmenau Universitätsbibliothek (Verlag)
978-3-86360-055-6 (ISBN)

Lese- und Medienproben

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In this thesis the application of AlGAN-based pH-sensors for fetal blood sampling is investigated. To gain insight into these sensors' electrical and sensory properties, AlGaN/GaN-heterostructures with metal- and electrolyte-contacts are characterised using impedance spectroscopy. An equivalent circuit employing constant phase elements is derived to account for the two-dimensional depletion characteristic of these heterostructures. Their pH-sensitivity is determined, various drift phenomena are characterised and optimisation steps aimed at improving sensor stability and measurement accuracy and precision are investigated. It is shown that an accuracy of ±0.03pH can be achieved for the determination of pH-value in aqueous solutions as well as umbilical cord blood. The results of this work are utilised for developing a micro-blood-pH analyser with a minimal sample volume of only 10 μl, which satisfies the accuracy and precision requirements of the German Medical Association guidelines.

Erscheint lt. Verlag	1.4.2013
Verlagsort	Ilmenau
Sprache	englisch
Maße	145 x 205 mm
Gewicht	450 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Laboratoriumsmedizin
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
	Naturwissenschaften ► Chemie ► Analytische Chemie
Schlagworte	Biosensor • Blut • Elektrochemischer Sensor • Nabelschnur • Wasserstoffionenkonzentration / Mikroanalyse / Ionensensitiver Feldeffekttransistor / Aluminiumnitrid / Galliumnitrid / Oxymetrie
ISBN-10	3-86360-055-X / 386360055X
ISBN-13	978-3-86360-055-6 / 9783863600556
Zustand	Neuware