Osteogenesis Imperfecta
Academic Press Inc (Verlag)
978-0-12-397165-4 (ISBN)
- Titel erscheint in neuer Auflage
- Artikel merken
Osteogenesis Imperfecta is the first translational reference professionals can turn to for a source of comprehensive information on this disorder. Although several reviews of the field have been published in various journals, there is no other single source for a compendium of current information. Separate chapters discuss each of the several clinical features of OI. Ethical issues related to OI are discussed, as is the importance of nutrition in managing the OI child and the OI adult. The role of physical medicine and rehabilitation for OI patients is also presented, along with the current status of OI medical treatment and the prospects for genetic engineering in the future. The text also provides the orthopedic surgeon with an advanced discussion of surgical techniques applicable to OI.
Dr. Jay R. Shapiro is a graduate of Franklin and Marshall College and the Boston University School of Medicine. He serves as Professor in the Department of Physical Medicine and Rehabilitation and Director of the Bone and Osteogenesis Imperfecta Department at the Kennedy Krieger Institute. He served as Director of the General Clinical Research Center at Johns Hopkins University and is on the Medical Advisory Committee of the Osteogenesis Imperfecta Foundation. Dr. Shapiro also served as the Chief for the Bone Team of the National Space Biomedical Research Institute. Dr. Shapiro has specialty interests in endocrine, metabolic and genetic disorders of bone. Current research activities include: heart disease in adult osteogenesis imperfecta, the effect of nutrition on bone growth in osteogenesis imperfecta, osteoporosis in Rett syndrome and a study of the effects of bisphosphonate treatment during microgravity on the International Space Station (NASA).
Foreword
Acknowledgments
List of Contributors
Section 1: INTRODUCTION
Section 2: BONE BIOLOGY, STRUCTURE AND BIOCHEMISTRY
Section 3: CLINICAL AND MOLECULAR GENETICS OF OSTEOGENESIS IMPERFECTA
Section 4: COL1A1 AND COL1A2 MUTATIONS
Section 5: ANIMAL MODELS OF OSTEOGENESIS IMPERFECTA
Section 6: BRITTLE BONE OVERLAP PHENOTYPES: TGF-BETA MUTATIONS AND BONE
Section 7: CLINICAL ASPECTS OF OSTEOGENESIS IMPERFECTA
Section 8: ORGAN INVOLVEMENT IN OSTEOGENESIS IMPERFECTA
Chapter 9: ORTHOPEDICS
Section 10: PHYSICAL MEDICINE AND REHABILITATION
Section 11: PHARMACOLOGIC TREATMENT OF OSTEOGENESIS IMPERFECTA
Section 12: GENETIC APPROACH TO TREATMENT OF OSTEOGENESIS IMPERFECTA
Index
| Erscheint lt. Verlag | 24.10.2013 |
|---|---|
| Mitarbeit |
Chef-Herausgeber: Javaid Kassim |
| Verlagsort | San Diego |
| Sprache | englisch |
| Maße | 216 x 276 mm |
| Gewicht | 1900 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Orthopädie |
| ISBN-10 | 0-12-397165-9 / 0123971659 |
| ISBN-13 | 978-0-12-397165-4 / 9780123971654 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
aus dem Bereich
