Lymphoid Organogenesis

Proceedings of the Workshop held at the Basel Institute for Immunology 5th–6th November 1999

Buch | Hardcover

XII, 215 Seiten

2000 | 2000
Springer Berlin (Verlag)
978-3-540-67569-3 (ISBN)

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It has been clear for a long time that after transplantation of a lymphoid organ, hematopoietic stem cells can regenerate the compartments of the organ, provided that the rest of its architecture - the strome, the epithelia and the vessels - is intact. Ahead lies the even greater challenge to assemble also these other architectural elements of a lymphoid organ by transplanting stem cells. The workshop on lymphoid organogenesis was convened to review current knowledge of and experimental skills involved in this grand project to build a lymphoid organ from its individual cellular components.

Human Mesenchymal Stem Cells: Progenitor Cells for Cartilage, Bone, Fat and Stroma.- Investigating the Genetic Control of Stem Cell Behavior.- Precursor B Cells from Pax-5-deficient Mice - Stem Cells for Macrophages, Granulocytes, Osteoclasts, Dendritic Cells, Natural Killer Cells, Thymocytes and T Cells.- Insertional Mutagenesis as a Route to Identifying Genes Involved in Self Renewal of Haemopoietic Stem Cells.- The Helix-Loop-Helix Inhibitor Id2 and Cell Differentiation Control.- Role of 131 Integrin for Hemato-Lymphopoiesis in Mouse Development.- The Ikaros Family and the Development of Early Intraembryonic Hematopoietic Stem Cells.- Function of Cytokines in Lymphocyte Development.- Re-evaluation of B Lymphocyte Lineage Differentiation Schemes.- Growth Factors Regulating Lymphatic Vessels.- Hemangioblastic Precursors in the Avian Embryo.- Cloning of JAM-2 and JAM-3: an Emerging Junctional Adhesion Molecular Family?.- Thymus Epithelial Cell Reaggregate Grafts.- A Novel Anti-Ep-CAM Antibody to Analyze the Organization of Thymic Medulla in Autoimmunity.- Genetic Dissection of Thymus Development.- Developing Thymocytes Organize Thymic Microenvironments.- The Role of Mesenchyme in Thymus Development.- Making Central T-Cell Tolerance Efficient: Thymic Stromal Cells Sample Distinct Self-Antigen Pools.- T Cell Activation and Polarization by DC 1 and DC2.- Functional Subsets of Memory T Cells Identified by CCR7 Expression.- Functional Organization of Secondary Lymphoid Organs by the Chemokine System.- The Cluster of ABCD Chemokines which Organizes T Cell-dependent B Cell Responses.- Affinity Maturation in Ectopic Germinal Centers.- Precursors to Neonatal Lymph Nodes: LT(3+CD45+CD4+CD3- Cells are Found in Fetal Liver.- The Role of Tumor Necrosis Factor and Lymphotoxin in Lymphoid Organ Development.

Erscheint lt. Verlag	4.9.2000
Reihe/Serie	Current Topics in Microbiology and Immunology
Zusatzinfo	XII, 215 p. 61 illus., 4 illus. in color.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Gewicht	504 g
Themenwelt	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
Schlagworte	Antigen • Chemokine • hemaotopoietic stem cells • lymphoid organs • Lymphozyt • Organogenese • Thymus • Transplantation
ISBN-10	3-540-67569-8 / 3540675698
ISBN-13	978-3-540-67569-3 / 9783540675693
Zustand	Neuware