Advances in Enzyme Regulation
Pergamon (Verlag)
978-0-08-042193-3 (ISBN)
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This internationally acclaimed annual series reports progress at the cutting edge in the strategic area of regulation at the molecular level. In an integrated presentation of original papers, leading scientists, Nobel Prize winners and other outstanding experts from many countries review the best research produced each year and evaluate what is newest and what promises to be the most important in clinical and basic investigations. The volumes serve as guideposts and beacons for investigators in planning research and teaching students in basic and clinical fields of endeavour. These books advance the general front of studies on metabolic regulation and the understanding of the molecular biology of control of gene expression by hormones, drugs and growth factors in cancer cells and in clinical situations of diabetes, inborn errors of metabolism and neoplasia.
Part 1 Chemotherapy and resistance: studies on the mechanisms of the cytotoxic ation of the mitomycin antibiotics in hypoxic and oxygenated EMT6 cells, A. Sartorelli et al; cellular resistance to alkylating agents, O.M. Colvin et al; effect of resistance on combination chemotherapy for human immunodeficiency virus infection, S.W. Cox et al. Part 2 Control of deoxycytidine kinase: regulation of deoxycytidine kinase activity, G. Weber et al; regulation of human deoxycytidine kinase expression and characterization of the gene, B.S. Mitchell et al. Part 3 Regulation of glocuse metabolism: mechanisms involved in the coordinate regulation of strategic enzymes of glucose metabolism, M.C. Sugden et al; fructose 2,6-bisphosphate and the control of glycolysis by growth factors, tumor promoters and oncogenes, L. Hue and G.G. Rousseau. Part 4 Enzymes as targets: drug resistance associated with altered DNA topoisomerase II, W.T. Beck et al; structural aspects of N-hydroxy-n'-aminoguanidine derivatives as inhibitors of L1210 cell growth and ribonucleotide reductase activity, J.G. Cory. Part 5 Mitogenic signalling and enzymology: early responses in mitogenic signalling; Bombesin induced protein phosphorylations in Swiss 3T3 cells, J. Van Lint et al; nuclear phosphoinositidase C during growth factor stimulation, L. Cocco et al. Part 6 Functions of protesomes and peroxisomes: regulation of protesome expression in developing and transformed cells, A. Ichihara et al; peroxisomal leukotriene degradation - biochemical and clinical implications, G. Jedlitschky et al. Part 7 Reaction mechanisms and enzymic properties: chemical modification of an arginine residue in aldose reductase is enhanced by coenzyme binding - further evidence for conformational change during the reaction mechanism, T.G. Flynn and T.J. Kubiseski; the properties and function of gamma-glutamyl hydrolase and poly-gamma-glutamate, Y. Wang et al. Part 8 Control of adenine nucleotides and nucleoside transport: the control of cellular adenine nucleotides - the discovery and metabolism of an oligomeric derivative of ATP and phosphoglyceric acid in mitochondrial intermembrane space, J. Mowbray and B. Patel; nucleoside transport in normal and neoplastic cells, J.A. Belt et al. Part 9 Molecular cloning, suppression of RAS and malignancy. Part 10 Special symposium lecture.
| Erscheint lt. Verlag | 31.7.1993 |
|---|---|
| Reihe/Serie | Advances in Enzyme Regulation ; Vol 33 |
| Zusatzinfo | 107 illustrations, 800 references, 21 halftones, indices |
| Verlagsort | Amsterdam |
| Sprache | englisch |
| Themenwelt | Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik |
| Naturwissenschaften ► Biologie ► Biochemie | |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| ISBN-10 | 0-08-042193-8 / 0080421938 |
| ISBN-13 | 978-0-08-042193-3 / 9780080421933 |
| Zustand | Neuware |
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