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The Engines of Hippocrates (eBook)

From the Dawn of Medicine to Medical and Pharmaceutical Informatics
eBook Download: PDF
2009 | 1. Auflage
512 Seiten
John Wiley & Sons (Verlag)
978-0-470-46179-2 (ISBN)

Lese- und Medienproben

The Engines of Hippocrates - Barry Robson, O. K. Baek
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A unique, integrative look at information-based medicine

The convergence of medical science, biology, pharmacology,
biomedical engineering, healthcare, and information technology is
revolutionizing medical and scientific practice, and has broader
social implications still being understood. The Engines of
Hippocrates provides a unique, integrative, and holistic look
at the new paradigm of information-based medicine, covering a broad
range of topics for a wide readership.

The authors take a comprehensive approach, examining the
prehistory, history, and future of medicine and medical technology
and its relation to information; how history led to such
present-day discoveries as the structure of DNA, the human genome,
and the discipline of bioinformatics; and what the future results
of these discoveries may hold. Their far-ranging views are their
own and not necessarily those of the IBM Corporation or other
employers.

The Engines of Hippocrates helps readers understand:

* Forces shaping the pharmaceutical and biomedical industries
today, including personalized medicine, genomics, data mining, and
bionanotechnology

* The relationship between pharmaceutical science today and other
disciplines such as philosophy of health, history, economics,
mathematics, and computer science

* The integrated role alternative and non-Western medicines could
play in a new, information-based medicine

* Practical, ethical, organizational, technological, and social
problems of information-based medicine, along with a novel
data-centric computing model and a self-adaptive software
engineering model, and corresponding information technology
architectures, including perspectives on sharing remote data
efficiently and securely for the common good

An unmatched, cross-disciplinary perspective on the big picture
of today and tomorrow's medicine, The Engines of Hippocrates
provides a reference to interested readers both inside and outside
the pharmaceutical and medical communities, as well as a peerless
classroom supplement to students in a wide variety of
disciplines.

BARRY ROBSON is Director of Medical Research and Professor of Biostatistics, Epidemiology, and Evidence Based Medicine at St. Matthew's University School of Medicine, and CEO of The Dirac Foundation, formed with the permission of Nobel laureate Paul A. M. Dirac's widow to promote understanding of the value of theoretical physics in human and veterinary medicine. Until recently, he was Chief Scientific Officer of IBM Global Healthcare and Life Sciences, and then Global Pharmaceutical and Life Sciences, an IBM Distinguished Engineer, and previously, Strategic Advisor at IBM Research headquarters. O. K. BAEK is a Senior Solutions Architect at IBM, specializing in healthcare and with a passionate interest in the benefits and long-standing logic of Oriental medicine. He is particularly interested in the development of novel architectures for sharing and using medical information securely, and in translational research, the matter of rapidly delivering the results of medical research and genomics to enhance everyday clinical decisions.

Preface.

About the Authors.

1 A Short Preview of Mankind, Medicine, Molecules, and
Machines.

2 From Prehistory to Hippocrates.

3 The Road to the New Medicine.

4 The Imminent Challenge: Medicine as an Industry.

5 The Next Decade: Personalized Medicine and the Digital Patient
Record.

6 Enforcing your Rights: Medical Ethics, Consent, Privacy, and
IT.

7 Holistic Medicine and IT.

8 Architecting It All.

9 Guardian Angels: Knowing Our Molecules, Drug and Vaccine
Design, Medical Decision Support, Medical Vigilance and
Defense.

10 What Next? At One with the Engines of Hippocrates.

Glossary.

Clinical Trial Terms.

Notes, Bibliography, and Further Reading Guide.

Index.

"We should not throw a stone to the authors for not having limited
the subject of this book to the necessity of digital records
running on computers for patients rightly waiting for a
personalized healthcare. Rather, the reader will also enjoy the
large spectrum of knowledge delivered through innumerable
digressions hopefully made re-accessible through a generous index.
Written with a witty journalistic style, this book lets itself read
like a novel rich in unexpected developments."

--Jean Garnier, Editor-in-Chief, Biophysical
Review

"In this book, Robson and Baek, both experts of the interface
between medicine and computer, led the reader to a journey
encompassing many disciplines. Though daunting at first, one cannot
help appreciate the perspective from history, health, philosophy,
economy, mathematics and IT. As history has shown, IT, along with
many other drug discovery technologies, contributed to the golden
age of the drug industry signified with the era of blockbuster
drugs. In today's environment with the paucity of blockbuster
drugs, one cannot help to wonder if drug discovery technologies
including IT should be attenuated or extenuated.

This book could not be out at a more opportune time. Americans are
now burdened with the crushing weight of healthcare cost. One of
the cost-saving measures, recognized by both President Obama and
the Congress, is digitization of medical records. In addition, this
book also covers topics such as patent-based drug design,
pharmacogenomics, medical vigilance, and many other gems. It is a
tribute to the authors' remarkable breadth of knowledge and
organizational skills to assemble them together. Anyone interested
in health care, especially the ones interested in pharmaceutical
informatics, would benefit from reading this book."

--Jie Jack Li

Erscheint lt. Verlag 28.5.2009
Reihe/Serie Wiley Series on Technologies for the Pharmaceutical
Wiley Series on Technologies for the Pharmaceutical
Mitarbeit Herausgeber (Serie): Sean Ekins
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Studium Querschnittsbereiche Geschichte / Ethik der Medizin
Naturwissenschaften Chemie
Schlagworte Bioinformatics & Computational Biology • Bioinformatik • Bioinformatik u. Computersimulationen in der Biowissenschaften • Biowissenschaften • Chemie • Chemistry • Drug Discovery & Development • Gesundheits- u. Sozialwesen • Health & Social Care • Health Care Administration • Life Sciences • Verwaltung im Gesundheitswesen • Wirkstoffforschung u. -entwicklung
ISBN-10 0-470-46179-9 / 0470461799
ISBN-13 978-0-470-46179-2 / 9780470461792
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