Process Scale Purification of Antibodies (eBook)

Uwe Gottschalk (Herausgeber)

eBook Download: PDF

2009 | 1. Auflage
456 Seiten
John Wiley & Sons (Verlag)
978-0-470-44488-7 (ISBN)

Infos

Traditional column chromatography dominates current purification technology, and many of the productivity gains that have been achieved have relied on upscaling such devices. However, this comes with a cost penalty and the pharmaceutical industry has reached the point at which further upscaling becomes economically unsupportable. This book offers a broad-based reassessment of old and new purification methods, incorporating an analysis of innovative new trends in purification. The book has wide coverage of different antibody purification strategies and brings together top-tier experts to address problems in process-scale antibody purification.

Autor

Uwe Gottschalk, PhD, is Group Vice President, Purification Technologies, at Sartorius Stedim Biotech. Previously, he worked for Bayer Health Care, overseeing the purification of monoclonal antibodies and recombinant proteins produced in various expression systems. Dr. Gottschalk received a doctorate in chemistry from the University of Münster. He lectures at the University of Duisburg-Essen and the EPFL in Lausanne, Switzerland and has written extensively in the areas of biotechnology and somatic gene therapy.

Produkt-Details

• Erscheint lt. Verlag: 26.3.2009
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie
• Themenwelt: Naturwissenschaften ► Chemie
• Schlagworte: Antikörper • Antikörper • Biochemie u. Chemische Biologie • Biochemistry (Chemical Biology) • biomedical engineering • Biomedizintechnik • Chemie • Chemistry • Drug Discovery & Development • Protein Engineering • Protein-Engineering • Wirkstoffforschung u. -entwicklung
• ISBN-10: 0-470-44488-6 / 0470444886
• ISBN-13: 978-0-470-44488-7 / 9780470444887