Endothelium

Molecular Aspects of Metabolic Disorders

Ayse Basak Engin, Atilla Engin (Herausgeber)

Buch | Hardcover

468 Seiten

2013
Crc Press Inc (Verlag)
978-1-4665-8279-8 (ISBN)

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The function and life span of endothelial cells have a large impact upon the quality and expectancy of an individual's life. During low perfusion, the adaptation of different cells to hypoxia precipitate the aggressive progression of diseases. Although the clinical studies have convincingly shown that endothelial dysfunction occurs whenever the biological functions or bioavailability of nitric oxide are impaired, in all these scenarios, the role of endothelial cell-destructive process cross-talk is yet poorly understood. This book focuses on the contribution of molecular mechanisms to endothelial dysfunction in related metabolic disorders.

Ayse Basak Engin, Atilla Engin

Physiological importance of endothelium. Vascular fluid mechanics in the regulation of endothelial function. Ultrastructure of endothelium and endothelial microparticules. Origin of endothelial progenitor cells and their functions. Endothelial dysfunction, cytokines and their genetic variations. Oxidative stress and endothelium: Cellular signaling, nitric oxide and reactive radicals. Asymmetric dimethylarginine and endothelial dysfunction. Endothelial Dysfunction and Diabetes Mellitus. Obesity, metabolic syndrome and endothelium. Vascular endothelium and renin-angiotensin system. Endothelial dysfunction in chronic kidney disease patients and renal transplant recipients: Emerging diagnostic and therapeutic options. Homocysteine and endothelial dysfunction. Oxidative stress and angiogensisis in tumor progression. Nanoparticle: As a messenger between environment and endothelium.

Zusatzinfo	5 Illustrations, color; 31 Illustrations, black and white
Verlagsort	Bosa Roca
Sprache	englisch
Maße	156 x 234 mm
Gewicht	816 g
Themenwelt	Medizin / Pharmazie ► Allgemeines / Lexika
	Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie
	Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie
	Studium ► 1. Studienabschnitt (Vorklinik) ► Anatomie / Neuroanatomie
	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
	Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
ISBN-10	1-4665-8279-0 / 1466582790
ISBN-13	978-1-4665-8279-8 / 9781466582798
Zustand	Neuware