Trace Elements, Micronutrients, and Free Radicals

Ivor E. Dreosti (Autor)

Buch | Softcover

231 Seiten

2012
Humana Press Inc. (Verlag)
978-1-4612-6754-6 (ISBN)

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Itisonlyrecently thatthe naturaloccurrenceoffree radicalsin biological tissue has become widely accepted, and that the suspi- cion with which biologists previously viewed the free radicals of radiationchemistryhas beenplacedin a broaderperspective. Now, oxygen-derived free radicals are considered respectable biochemi- cal intermediates, given always the caveat that unwanted tissue damage may arise if these active species are produced in such abundance that they overwhelm the natural antioxidant and free- radical defense mechanisms, or if these systems have become hypoeffective. Many factors, including several dietary manipula- tions, can lead toelevatedproductionofsuperoxide and may result in free radical overload, whereas a deficiency of those micronutri- ents associated with the antioxidant defense mec.hanisms may re- sult in substantially diminished antioxidant capacity. By now, antioxidants have become a household word and al- most everyone is aware of their imponance in protecting the body against attack by active oxygen species. Indeed, it is a paradox of nature that oxygen, which is so essential to sustain aerobic life, ul- timately contributes to its destruction.
Not surprisingly, recogni- tion ofthis dilemma has generated a spate ofantioxidant strategies intended to reduce the risk of tissue damage by rampant oxygen radicals, some sadly based less on science than on speculation.

1 • Free Radicals in Biological Systems.- 2 • Free Radicals as Mediators of Tissue Injury.- 3 • Free Radical Biology of Iron.- 4 • Dietary Prooxidants.- 5 • Essential Trace Elements in Antioxidant Processes.- 6 • Vitamins and Related Dietary Antioxidants.- 7 • Free Radical Pathology and the Genome.- 8 • The Role of Free Radicals in Cancer and Aging T..- 9 • Free Radicals and Malnutrition.- Conclusions.

...Highly recommend[ed].-Journal of Medicinal Chemistry

Reihe/Serie	Contemporary Issues in Biomedicine, Ethics, and Society
Zusatzinfo	VIII, 231 p.
Verlagsort	Totowa, NJ
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Studium ► 1. Studienabschnitt (Vorklinik)
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	1-4612-6754-4 / 1461267544
ISBN-13	978-1-4612-6754-6 / 9781461267546
Zustand	Neuware