Muscle Biopsy: A Practical Approach
W B Saunders Co Ltd (Verlag)
978-0-7020-4340-6 (ISBN)
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2014 BMA Medical Book Awards Highly Commended in Pathology category!
Muscle Biopsy: A Practical Approach gives you all of the unparalleled guidance necessary to effectively interpret and diagnose muscle biopsy specimens for the full range of diseases in both adults and children. Authored by Dr. Victor Dubowitz, an internationally renowned figure in the field of muscle disease, this medical reference book takes an integrated approach to diagnosis and assessment of muscle biopsies that includes clinical, genetic, biochemical, and pathological features. It's the comprehensive, up-to-date coverage you need to evaluate muscle disorders with confidence.
"Overall, this is a well written and comprehensive textbook of muscle pathology that will be of invaluable assistance to laboratories reporting muscle pathology" Reviewed by The Bulletin of The Royal College of Pathologists, Jan 2015
Bridge the gap between clinical syndromes/disorders and their underlying pathologies with the guidance of muscle disease expert, Dr. Victor Dubowitz, who skillfully guides you through the complexities of pathologic diagnoses and their implications for clinical treatment.
Understand and apply expert techniques for obtaining a muscle biopsy, and familiarize yourself with the histochemical, histological, electron microscopical, and molecular appearance of normal muscle and the pathology of individual muscle disease.
Read the entire contents and download all of the images online at Expert Consult.
Apply all of the latest diagnostic techniques for neurodegenerative and genetic diseases with a brand-new chapter on myopathies associated with systemic disorders and aging, and use advanced techniques such as immunohistochemistry and immunoblotting to produce the most accurate diagnoses possible for a full range of muscle disorders.
Stay current in practice with state-of-the-art coverage of genetic markers for individual conditions and antibodies used in immunocytochemical diagnosis.
Understand the genetics of muscular dystrophies with absolute clarity through the use of brilliantly simple diagrams and tables, and compare your specimens to a wealth of superb color images capturing the full spectrum of muscle biopsy findings.
Take advantage of international insights and fresh perspectives in muscle diseases and disorders from new author Dr. Anders Oldfors, from the Department of Pathology, University of Goteborg, Sweden.
Section 1 The Biopsy: Normal and Diseased Muscle
1. The procedure of muscle biopsy
2. Histological and histochemical stains and reactions
3. Normal muscle
4. Definition of pathological changes seen in muscle biopsies
5. Ultrastructural changes in diseased muscle
6. Immunohistochemistry
7. How to read a biopsy
Section 2 Pathological Muscle: Individual Diseases
8. Classification of neuromuscular disorders
9. Neurogenic disorders
10. Muscular dystrophies and allied disorders I: Duchenne and Becker muscular dystrophy
11. Muscular dystrophies and allied disorders II: limb-girdle muscular dystrophies
12. Muscular dystrophies and allied disorders III: congenital muscular dystrophies
13. Muscular dystrophies and allied disorders IV: Emeryf{Driefuss muscular dystrophies and Bethlem myopathy
14. Muscular dystrophies and allied disorders V: facioscapulohumeral dystrophy, myotonic dystrophy, oculopharyngeal muscular dystrophy
15. Congenital myopathies
16. Myofibrillar myopathies
17. Metabolic myopathies I: glycogenoses
18. Metabolic myopathies II: lipid related disorders and mitochondrial myopathies
19. Endocrine disorders
20. Ion channel disorders
21. Myasthenic syndromes
22. Inflammatory myopathies
23. Toxic and drug-induced myopathies
Russell Lane, Charing Cross Hospital
Appendix 1. Glossary of commonly used terms
References
Index
Erscheint lt. Verlag | 5.4.2013 |
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Zusatzinfo | Approx. 690 illustrations (538 in full color) |
Verlagsort | London |
Sprache | englisch |
Maße | 184 x 260 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Orthopädie |
Studium ► 2. Studienabschnitt (Klinik) ► Pathologie | |
ISBN-10 | 0-7020-4340-0 / 0702043400 |
ISBN-13 | 978-0-7020-4340-6 / 9780702043406 |
Zustand | Neuware |
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