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Muscle Biopsy: A Practical Approach - Victor Dubowitz, Caroline A. Sewry, Anders Oldfors

Muscle Biopsy: A Practical Approach

Expert Consult; Online and Print
Buch | Hardcover
592 Seiten
2013 | 4th Revised edition
W B Saunders Co Ltd (Verlag)
978-0-7020-4340-6 (ISBN)
CHF 299,95 inkl. MwSt
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Offers the guidance necessary to effectively interpret and diagnose muscle biopsy specimens for the full range of diseases in both adults and children. It takes an integrated approach to diagnosis and assessment of muscle biopsies that includes clinical, genetic, biochemical, and pathological features.
2014 BMA Medical Book Awards Highly Commended in Pathology category!

Muscle Biopsy: A Practical Approach gives you all of the unparalleled guidance necessary to effectively interpret and diagnose muscle biopsy specimens for the full range of diseases in both adults and children. Authored by Dr. Victor Dubowitz, an internationally renowned figure in the field of muscle disease, this medical reference book takes an integrated approach to diagnosis and assessment of muscle biopsies that includes clinical, genetic, biochemical, and pathological features. It's the comprehensive, up-to-date coverage you need to evaluate muscle disorders with confidence.

"Overall, this is a well written and comprehensive textbook of muscle pathology that will be of invaluable assistance to laboratories reporting muscle pathology" Reviewed by The Bulletin of The Royal College of Pathologists, Jan 2015



Bridge the gap between clinical syndromes/disorders and their underlying pathologies with the guidance of muscle disease expert, Dr. Victor Dubowitz, who skillfully guides you through the complexities of pathologic diagnoses and their implications for clinical treatment.
Understand and apply expert techniques for obtaining a muscle biopsy, and familiarize yourself with the histochemical, histological, electron microscopical, and molecular appearance of normal muscle and the pathology of individual muscle disease.
Read the entire contents and download all of the images online at Expert Consult.



Apply all of the latest diagnostic techniques for neurodegenerative and genetic diseases with a brand-new chapter on myopathies associated with systemic disorders and aging, and use advanced techniques such as immunohistochemistry and immunoblotting to produce the most accurate diagnoses possible for a full range of muscle disorders.
Stay current in practice with state-of-the-art coverage of genetic markers for individual conditions and antibodies used in immunocytochemical diagnosis.
Understand the genetics of muscular dystrophies with absolute clarity through the use of brilliantly simple diagrams and tables, and compare your specimens to a wealth of superb color images capturing the full spectrum of muscle biopsy findings.
Take advantage of international insights and fresh perspectives in muscle diseases and disorders from new author Dr. Anders Oldfors, from the Department of Pathology, University of Goteborg, Sweden.

Section 1 The Biopsy: Normal and Diseased Muscle

1. The procedure of muscle biopsy

2. Histological and histochemical stains and reactions

3. Normal muscle

4. Definition of pathological changes seen in muscle biopsies

5. Ultrastructural changes in diseased muscle

6. Immunohistochemistry

7. How to read a biopsy


Section 2 Pathological Muscle: Individual Diseases

8. Classification of neuromuscular disorders

9. Neurogenic disorders

10. Muscular dystrophies and allied disorders I: Duchenne and Becker muscular dystrophy

11. Muscular dystrophies and allied disorders II: limb-girdle muscular dystrophies

12. Muscular dystrophies and allied disorders III: congenital muscular dystrophies

13. Muscular dystrophies and allied disorders IV: Emeryf{Driefuss muscular dystrophies and Bethlem myopathy

14. Muscular dystrophies and allied disorders V: facioscapulohumeral dystrophy, myotonic dystrophy, oculopharyngeal muscular dystrophy

15. Congenital myopathies

16. Myofibrillar myopathies

17. Metabolic myopathies I: glycogenoses

18. Metabolic myopathies II: lipid related disorders and mitochondrial myopathies

19. Endocrine disorders

20. Ion channel disorders

21. Myasthenic syndromes

22. Inflammatory myopathies

23. Toxic and drug-induced myopathies
Russell Lane, Charing Cross Hospital


Appendix 1. Glossary of commonly used terms


References


Index

Erscheint lt. Verlag 5.4.2013
Zusatzinfo Approx. 690 illustrations (538 in full color)
Verlagsort London
Sprache englisch
Maße 184 x 260 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Orthopädie
Studium 2. Studienabschnitt (Klinik) Pathologie
ISBN-10 0-7020-4340-0 / 0702043400
ISBN-13 978-0-7020-4340-6 / 9780702043406
Zustand Neuware
Informationen gemäß Produktsicherheitsverordnung (GPSR)
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