Reassessing HIV Vaccine Design & Approaches

Towards a Paradigm Shift

Omar Bagasra, Donald Gene Pace (Herausgeber)

Buch | Hardcover

369 Seiten

2013
Nova Science Publishers Inc (Verlag)
978-1-62257-952-5 (ISBN)

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Why do we not have a vaccine for HIV? What are we doing wrong? Every HIV vaccine has failed so far, and public opinion is turning pessimistic against the scientific community. HIV vaccine efforts need a major shift in strategy. They require a better understanding of the immunological mechanisms that prevent African primates from getting AIDS. None of the 40 species of African primates, including chimpanzees and gorillas, get AIDS, even though all of them carry HIV-like viruses in their bodies. Why are they "naturally vaccinated," while all of the man-made vaccines against HIV have failed miserably? This book offers intriguing new possibilities for the nature of human immunity, and the development of an effective AIDS vaccine. It is also a provocative treatise on the origin, evolution, and etiology of several forms of immune systems that is supported by a wealth of peer-reviewed scientific references. The compelling ideas presented in this study should have an important bearing on HIV vaccine development. It is a must read for anyone interested in the development of a safe AIDS vaccine, and for individuals interested in human immunity generally.

Preface; A Shift in the Current Concept of HIV Vaccine; Immunity: Old Paradigm Versus New; The Architecture of the Classical Immune System; Origins of HIV-1; A Unified Concept of HIV Latency, Persistence & Reservoirs; Immune Activation & MicroRNA; GBV-C: A Natural HIV Interfering Virus; HIV Prevention & Compounding Factors in Chronic Progression to AIDS; Epilogue; References; Index.

Verlagsort	New York
Sprache	englisch
Maße	180 x 260 mm
Gewicht	718 g
Themenwelt	Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie
ISBN-10	1-62257-952-6 / 1622579526
ISBN-13	978-1-62257-952-5 / 9781622579525
Zustand	Neuware