PAKs, RAC/CDC42 (p21)-activated Kinases
Towards the Cure of Cancer and Other PAK-dependent Diseases
Seiten
2013
Elsevier Science Publishing Co Inc (Verlag)
978-0-12-407198-8 (ISBN)
Elsevier Science Publishing Co Inc (Verlag)
978-0-12-407198-8 (ISBN)
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Covers a variety of basic and clinical PAK research ranging from laboratory benches to hospital beds. This book consists of 9 chapters which deal with different aspects of this kinase. It describes a number of PAK blockers which would be useful for the therapy of these PAK-dependent diseases, and some of them are available on the market.
This book covers a variety of cutting-edge basic and clinical PAK research ranging from laboratory benches to hospital beds. The goal of this book is to inspire not only biomedical research scientists and university students, but also a variety of patients who suffer from PAK-dependent diseases and clinical doctors who try to cure or delay these PAK-dependent diseases.This book consists of 9 chapters which deal with different aspects of this kinase. These chapters are written by more than two dozen world-leading PAK experts. Each of these will provide updated biomedical information as well as future insight to a wide range of readers who are interested in this unique kinase and both its pathological and physiological roles as well as its functional evolution from its ancestral origins.
This book covers a variety of cutting-edge basic and clinical PAK research ranging from laboratory benches to hospital beds. The goal of this book is to inspire not only biomedical research scientists and university students, but also a variety of patients who suffer from PAK-dependent diseases and clinical doctors who try to cure or delay these PAK-dependent diseases.This book consists of 9 chapters which deal with different aspects of this kinase. These chapters are written by more than two dozen world-leading PAK experts. Each of these will provide updated biomedical information as well as future insight to a wide range of readers who are interested in this unique kinase and both its pathological and physiological roles as well as its functional evolution from its ancestral origins.
1. Functional Maturation of PAKs2. Oncogenicity of PAKs and Their Substrates3. Natural or Synthetic Therapeutics that Block PAKs4. PAK1 in Parasites-Host Interaction5. PAK1 in Brain Diseases6. PAK1 in Alzheimer’s and Huntington’s diseases7. PAK1 Controls the Lifespan8. PAK 4-6 in Cancer and Neuronal Development
| Erscheint lt. Verlag | 1.2.2013 |
|---|---|
| Sprache | englisch |
| Maße | 152 x 229 mm |
| Gewicht | 390 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete |
| Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie | |
| Naturwissenschaften ► Biologie ► Biochemie | |
| Naturwissenschaften ► Chemie | |
| ISBN-10 | 0-12-407198-8 / 0124071988 |
| ISBN-13 | 978-0-12-407198-8 / 9780124071988 |
| Zustand | Neuware |
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