The Science and Ethics of Engineering the Human Germ Line (eBook)

Mendel's Maze

Jon W. Gordon (Autor)

eBook Download: PDF

2003 | 1. Auflage
304 Seiten
John Wiley & Sons (Verlag)
978-0-471-47820-1 (ISBN)

Infos

With implications that go to the core of what it means to be human,
the issues raised by genetic manipulation-especially cloning-have
sparked a passionate debate among governmental, religious, and
scientific quarters, as well as the media and the general public.
Keeping to the actual science rather than speculation is of the
utmost importance for an enlightened approach to this weighty
discussion.

In clear, lively prose, The Science and Ethics of
Engineering the Human Germ Line: Mendel's Maze provides an
authoritative treatment of the principles of science and bioethics
that bear upon such technologies as germ-line insertion and
cloning. It offers a realistic assessment of possible applications,
limitations, and new developments likely to arise in these
areas.

Written by a top physician-investigator, this book progresses
from the basics of building a living organism from inanimate parts
through to recombinant DNA technology, assisted reproductive
technologies, and gene transfer and germ-line engineering. Ethical
considerations are woven into this material throughout, while a
special section covers the intellectual role played by various
social biases.

As genetic and reproductive technologies spread from the
laboratory to the clinic-and society takes further notice-students
and practitioners of biology and medicine, as well as the
interested general reader, will find The Science and Ethics
of Engineering the Human Germ Line: Mendel's Maze to be an
essential and accessible guide to these important subjects.

Autor

Dr. Gordon graduated from Columbia University with a major in Biology in 1971. He obtained a Ph.D. Yale University in 1978, receiving an award for the best Ph.D. thesis in Biology that year. In 1980 Dr. Gordon graduated with honors from Yale University Medical School. In the two years following medical school Dr. Gordon, in collaboration with Frank H. Ruddle at Yale University, produced the first "transgenic" mouse, a mouse with genes from another species inserted into the germ line. Since then he has pioneered new techniques for assisting fertilization in human in vitro fertilization and has published many research papers, reviews and opinion papers on the science and ethics of gene transfer and related reproductive technologies. He is an internationally recognized authority in the area of germ line gene transfer.

Inhalt

Preface.

Acknowledgments.

PART I.

1. Setting the Table.

2. Building a Living Organism from Inanimate Parts.

3. Molecular Biology and Recombinant DNA Technology.

4. Transmitting the Genetic Information to Future
Generations.

5. Developmental Biology.

6. Reproductive Biology and Assisted Reproductive
Technologies.

7. Methods and Strategies for Gene Transfer and Engineering of
the Germ Line.

PART II.

8. Introduction to the Ethics of Reproductive Genetic
Technologies.

9. Future Developments and Applications of Genetic Engineering
Technology.

10. What If? Ethical and Legal Aspects of Germ Line Genetic
Manipulation.

A Brief Epilogue: Understanding Our Biases.

Index.

Rezensionen

"...will help us engage in a sensible and productive discussion to
decide collectively the role genetic technologies should play in
our future." (The Quarterly Review of Biology, December
2004)

"Academic, hospital, and corporate health sciences libraries
would welcome this title as an asset to their collections."
(E-STREAMS, July 2004)

"...an essential and accessible guide to these important
subjects. Dr. Gordon and John-Wiley Corporation jointly deserve a
pat in the back for producing a beneficial and 'eye-opening' book."
(Annals of Biomedical Engineering, August 2004)

"...elucidates the background of genetic manipulation for
the layman...recommended..." (Choice, Vol. 41, No. 8,
April 2004)

"...this book succeeds in demystifying many of the issues
surrounding germline genetic manipulations..." (Science
Books & Films, April 2004)

"This powerful ethical message, combined with Gordon's
scientific acumen, make for a simultaneously accessible and
thoughtful book." (Yale Journal of Biology and Medicine,
July 2003)

Produkt-Details

• Erscheint lt. Verlag: 24.9.2003
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Medizinethik
• Themenwelt: Studium ► Querschnittsbereiche ► Geschichte / Ethik der Medizin
• Themenwelt: Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
• Themenwelt: Technik
• Schlagworte: biomedical engineering • Biomedizintechnik • Biotech & Gene Technology • Biotechnologie- u. Gentechnikrecht • Biowissenschaften • Ethik • Genetics • Genetik • Law • Life Sciences • Medizin • Rechtswissenschaft • Tissue, Cell, and Genetic Engineering • Zell-, Gewebe- u. Gen-Engineering
• ISBN-10: 0-471-47820-2 / 0471478202
• ISBN-13: 978-0-471-47820-1 / 9780471478201